- Basic information
- CohesinDB ID: CDBP00419738
- Locus: chr21-40373645-40374855
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Data sourse: ENCSR000BTQ, GSE206145-GSE177045, GSE72082, ENCSR404BPV, ENCSR703TNG
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Cell type: MCF-7, Neurons-H1
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 1% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.978
- Subunit: Mau2,SMC3,Rad21
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CTCF binding site: non-CTCF
CTCF motif: False
- Genomic location: Intragenic
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: Hub
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Hi-C loops: True
Hi-ChIP loops: False
ChIA-PET loops: True
- Compartment:
33% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): True
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Chromatin annotation:
"15_Quies": 78%,
"9_Het": 8%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: PGR, CBX1, FOXA2, NKX2-2, SIN3A, SOX2, CTBP1, FOXA1, BAHD1, RELA, CREBBP, ZXDC, RAD21, ARNT, HIF1A, GATA3, PRDM9, STAT3, SMARCE1, FOXM1, NKX3-1, FOS, MTA1, MED1, TLE3, CEBPB, NCOA3, NR2F2, TEAD1, CREB1, TCF7L2, TFAP2C, PIAS1, ZNF217, ESR1, KLF9, JUN, TCF12, ZHX2, EP300, USF1, AR, HDAC2, GATA2, RAD51, CTBP2, SCRT1, MBD2, TEAD4, PDX1, AHR, FOSL2
- Target gene symbol (double-evidenced CRMs): SH3BGR,GET1-SH3BGR
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 8
- Number of somatic mutations (non-coding): 3
- Related genes and loops