- Basic information
- CohesinDB ID: CDBP00419741
- Locus: chr21-40389621-40390661
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Data sourse: ENCSR000BTQ, GSE72082, ENCSR404BPV, ENCSR198ZYJ, ENCSR703TNG, GSE25021
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Cell type: MCF-7, Neurons-H1
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 2% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.978
- Subunit: SMC3,Rad21,SA1
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CTCF binding site: CTCF
CTCF motif: False
- Genomic location: TES,Intragenic
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: Hub
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Hi-C loops: True
Hi-ChIP loops: True
ChIA-PET loops: True
- Compartment:
33% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): True
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Chromatin annotation:
"15_Quies": 81%,
"9_Het": 9%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: CBX1, CHD8, MYCN, ZFX, XBP1, DUX4, RELA, MYC, ZKSCAN2, GRHL3, GATA3, PRDM9, ZNF736, ZNF592, NCOA3, EZH2, ZNF687, SETDB1, CTCF, EP300, BRD4, GTF2F1, STAG1
- Target gene symbol (double-evidenced CRMs): PCP4
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 9
- Number of somatic mutations (non-coding): 9
- Related genes and loops
- Related gene:
ENSG00000183036,
- Related loop:
chr21:39775000-39800000~~chr21:40375000-40400000,
chr21:39787674-39789450~~chr21:40385781-40387172,
chr21:39850000-39875000~~chr21:40375000-40400000,
chr21:39900000-39925000~~chr21:40375000-40400000,
chr21:40125000-40150000~~chr21:40375000-40400000,
chr21:40143203-40145143~~chr21:40385550-40387260,
chr21:40143209-40145089~~chr21:40385777-40387210,
chr21:40143216-40145182~~chr21:40385497-40387239,
chr21:40143218-40145094~~chr21:40385505-40387214,
chr21:40143220-40145193~~chr21:40385428-40387263,
chr21:40143223-40145165~~chr21:40385500-40387251,
chr21:40143235-40145160~~chr21:40385101-40387258,
chr21:40143236-40145155~~chr21:40385794-40387196,
chr21:40143254-40145149~~chr21:40385829-40387199,
chr21:40143256-40145192~~chr21:40385428-40387257,
chr21:40143258-40145166~~chr21:40385841-40387219,
chr21:40143263-40145135~~chr21:40385795-40387254,
chr21:40143268-40144900~~chr21:40385471-40387249,
chr21:40145591-40147301~~chr21:40385508-40387221,
chr21:40150000-40175000~~chr21:40375000-40400000,
chr21:40173092-40174823~~chr21:40385428-40387263,
chr21:40173269-40174874~~chr21:40385101-40387258,
chr21:40275000-40300000~~chr21:40375000-40400000,