- Basic information
- CohesinDB ID: CDBP00419746
- Locus: chr21-40403900-40404965
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Data sourse: ENCSR000BTQ, GSE206145-GSE177045, GSE72082, ENCSR404BPV, ENCSR198ZYJ, ENCSR703TNG, GSE25021
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Cell type: MCF-7, Neurons-H1
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 4% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.978
- Subunit: Mau2,SMC3,Rad21,SA1
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CTCF binding site: CTCF
CTCF motif: False
- Genomic location: Intragenic
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: Hub
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Hi-C loops: True
Hi-ChIP loops: False
ChIA-PET loops: True
- Compartment:
33% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): True
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Chromatin annotation:
"15_Quies": 80%,
"7_Enh": 10%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: RUNX1, PGR, CBX1, CHD8, FOXA2, NKX2-2, POU2F2, TOP2A, XBP1, FOXA1, FOXF1, DDX5, HOXB13, ERG, RELA, CREBBP, AHR, MYC, RFX1, RAD21, ARNT, HIF1A, NKX2-1, GATA3, GABPA, STAT3, MAX, MAFB, NKX3-1, NCOA3, CREB1, PIAS1, ETV1, STAG1, EZH2, ESR1, ZNF687, GRHL2, CTCF, EP300, BAF155, MNT, AR, DPF2, ZBTB40, GATA2, REST, EGLN2, ATF7, ASH2L, BRD4, FOXP1, SMC3, PDX1, RBPJ
- Target gene symbol (double-evidenced CRMs): .
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 15
- Number of somatic mutations (non-coding): 0
- Related genes and loops