- Basic information
- CohesinDB ID: CDBP00419754
- Locus: chr21-40443976-40444602
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Data sourse: GSE206145-GSE177045, GSE72082, ENCSR703TNG, GSE25021, GSE115602
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Cell type: MCF-7
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 2% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.989
- Subunit: Mau2,SA1,Rad21,SMC1
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CTCF binding site: non-CTCF
CTCF motif: False
- Genomic location: Intragenic
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: Hub
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Hi-C loops: True
Hi-ChIP loops: False
ChIA-PET loops: True
- Compartment:
33% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): False
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Chromatin annotation:
"15_Quies": 72%,
"9_Het": 23%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: PGR, XBP1, FOXA1, DPF1, SMARCE1, MITF, TEAD1, ETV1, ZNF217, ESR1, PITX3, JUN, CTCF, TCF12, BAF155, EP300, MNT, DPF2, IRF4, RFX5, RAD51, TEAD4, PDX1, TFAP2C, POU2F2, NANOG, CTBP1, DUX4, HNF4G, ERG, RAD21, NKX3-1, RCOR1, NR3C1, ESRRA, CEBPB, CREB1, GRHL2, EBF3, TRPS1, HDAC2, GATA2, GATAD2B, SREBF1, MXI1, SMARCA5, NCOA2, RUNX1, CBX1, MAFG, NKX2-2, SIN3A, CREBBP, ZXDC, ARNT, NFIB, FOXM1, MAFB, FOS, MED1, PIAS1, NCOA1, SETDB1, MAFK, USF1, TFAP2A, NIPBL, ARID1A, RBM25, CTBP2, MBD2, FOXP1, STAG1, FOXA2, CHD2, MAFF, HOXB13, KDM1A, RELA, BRG1, HIF1A, GATA3, TAL1, NRIP1, GATA1, ZNF143, HAND2, TLE3, NCOA3, NR2F2, TCF7L2, NR2F1, TP53, PKNOX1, PHOX2B, AR, MAML3, BRD4, CLOCK, CUX1, ZNF24, AHR, FOSL2
- Target gene symbol (double-evidenced CRMs): .
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 5
- Number of somatic mutations (non-coding): 0
- Related genes and loops