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Basic information

CohesinDB ID: CDBP00419755

Locus: chr21-40445230-40446041

Data sourse: ENCSR000BTQ, GSE206145-GSE177045, GSE72082, GSE76893, ENCSR000BLY, ENCSR000EHX, ENCSR703TNG, GSE25021

Cell type: MCF-7, SK-N-SH

DNA Sequence of binding site: UCSC hg38

Cohesin category

Peak occupancy ratio: 2% samples have this site.

Cell specificity (0: conserved, 1: cell type specific): 0.978

Subunit: NIPBL,SA1,Rad21,Mau2

CTCF binding site: non-CTCF CTCF motif: False

Genomic location: Intragenic

3D genome

TAD boundary: Boundary

Chromatin hubs: Hub

Hi-C loops: True Hi-ChIP loops: False ChIA-PET loops: True

Compartment: 33% Hi-C samples shows Compartment A

Cis-regulatory elements

Enhancer (Fantom5): non-Enhancer

Super enhancer (SEdb): False

Chromatin annotation: "15_Quies": 79%, "9_Het": 14%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).

Co-bound Transcriptional factors: PGR, XBP1, FOXA1, DPF1, SMARCE1, MITF, TEAD1, ETV1, ZNF217, ESR1, PITX3, JUN, CTCF, TCF12, BAF155, EP300, MNT, DPF2, IRF4, RFX5, RAD51, TEAD4, PDX1, TFAP2C, POU2F2, NANOG, CTBP1, DUX4, HNF4G, ERG, RAD21, NKX3-1, RCOR1, NR3C1, ESRRA, CEBPB, CREB1, GRHL2, EBF3, TRPS1, HDAC2, GATA2, GATAD2B, SREBF1, MXI1, SMARCA5, NCOA2, RUNX1, CBX1, MAFG, NKX2-2, SIN3A, CREBBP, ZXDC, ARNT, NFIB, FOXM1, MAFB, FOS, MED1, PIAS1, NCOA1, SETDB1, MAFK, USF1, TFAP2A, NIPBL, ARID1A, RBM25, CTBP2, MBD2, FOXP1, STAG1, FOXA2, CHD2, MAFF, HOXB13, KDM1A, RELA, BRG1, HIF1A, GATA3, TAL1, NRIP1, GATA1, ZNF143, HAND2, TLE3, NCOA3, NR2F2, TCF7L2, NR2F1, TP53, PKNOX1, PHOX2B, AR, MAML3, BRD4, CLOCK, CUX1, ZNF24, AHR, FOSL2

Target gene symbol (double-evidenced CRMs): .

Function elements

Human SNPs: .

Number of somatic mutations (coding): 4

Number of somatic mutations (non-coding): 0

Related genes and loops

Related gene:

eachgene

Deatailed information for cohesin site CDBP00419755