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Basic information

CohesinDB ID: CDBP00419756

Locus: chr21-40452725-40454179

Data sourse: GSE120943, ENCSR198ZYJ, ENCSR404BPV, GSE98367

Cell type: Neurons-H1, Monocytes, Macrophage

DNA Sequence of binding site: UCSC hg38

Cohesin category

Peak occupancy ratio: 1% samples have this site.

Cell specificity (0: conserved, 1: cell type specific): 0.967

Subunit: SMC3,Rad21,SMC1

CTCF binding site: non-CTCF CTCF motif: False

Genomic location: Intragenic

3D genome

TAD boundary: Boundary

Chromatin hubs: Hub

Hi-C loops: True Hi-ChIP loops: True ChIA-PET loops: True

Compartment: 33% Hi-C samples shows Compartment A

Cis-regulatory elements

Enhancer (Fantom5): non-Enhancer

Super enhancer (SEdb): False

Chromatin annotation: "15_Quies": 78%, "9_Het": 8%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).

Co-bound Transcriptional factors: RUNX1, PGR, NKX2-2, TOP2A, POU4F2, XBP1, FOXA1, ZNF823, CDK9, HOXB13, ERG, RELA, MYC, ARNT, HIF1A, NKX2-1, GATA3, GABPA, STAT3, MAX, ZSCAN4, NRIP1, NKX3-1, MITF, MED1, TLE3, NR3C1, NCOA3, TEAD1, CREB1, EZH2, ESR1, PITX3, SETDB1, BAF155, EP300, BCL11A, MNT, AR, REST, GATA2, IRF4, SIX2, BRD4, FOXP1, HEXIM1-CDK9, NCOA2

Target gene symbol (double-evidenced CRMs): RIPK4

Function elements

Human SNPs: .

Number of somatic mutations (coding): 14

Number of somatic mutations (non-coding): 0

Related genes and loops

Related gene: ENSG00000183421,

eachgene

Deatailed information for cohesin site CDBP00419756