- Basic information
- CohesinDB ID: CDBP00419759
- Locus: chr21-40465648-40468547
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Data sourse: ENCSR000BLD, GSE206145-GSE177045, GSE104888, ENCSR230ZWH, GSE72082, ENCSR501LQA, ENCSR760NPX, ENCSR000BLY, ENCSR404BPV, ENCSR150EFU, GSE105028, GSE103477, GSE111537, GSE131606, ENCSR330ELC, ENCSR000EDW, GSE25021, ENCSR000BUC, ENCSR917QNE, ENCSR000EFJ, GSE115602, GSE93080, GSE115250, GSE138405, GSE76893, GSE101921, ENCSR806UKK, GSE51234, ENCSR198ZYJ, GSE112028, GSE130135, ENCSR199XBQ, ENCSR703TNG, GSE138105, GSE145327, ENCSR895JMI, ENCSR000EEG, GSE98367, ENCSR193NSH, ENCSR768DOX, ENCSR000BLS, ENCSR000EHW, GSE85526, ENCSR000ECE, ENCSR247LSH, ENCSR807WAC, ENCSR000EHX, ENCSR620NWG, ENCSR635OSG, ENCSR748MVX, ENCSR767DFK, ENCSR495WGO, ENCSR981FDC, ENCSR984DZW, GSE97394, ENCSR217ELF, ENCSR000BTQ, GSE105004, ENCSR853VWZ, ENCSR956LGB, ENCSR944ZCT, GSE131956, GSE110061, ENCSR000HPG, ENCSR676MJK, ENCSR335RKQ, ENCSR054FKH, ENCSR537EFT, ENCSR000EDE, GSE206145, GSE126990, ENCSR000ECS, GSE131577
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Cell type: MDM, SLK, Liver, GP5d, TC-32, H9-hESC, RPE, HMEC, HEKn, HeLa-S3, IMR-90, DKO, H1-hESC, GM12878, GBM39, SK-N-SH, HeLa-Tet-On, THP-1, Macrophage, HUES64, MCF-7, Hela-Kyoto, HCT-116, HL-60, HEK293T, Hep-G2, Neurons-H1, A-549, HeLa, OCI-AML-3
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 37% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.656
- Subunit: NIPBL,SA1,Rad21,SMC1,SA2,Mau2,SMC3
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CTCF binding site: CTCF
CTCF motif: True
- Genomic location: Intragenic
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: Hub
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Hi-C loops: True
Hi-ChIP loops: True
ChIA-PET loops: True
- Compartment:
33% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): False
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Chromatin annotation:
"15_Quies": 74%,
"14_ReprPCWk": 13%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: WT1, ZFX
- Target gene symbol (double-evidenced CRMs): RIPK4
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 22
- Number of somatic mutations (non-coding): 0
- Related genes and loops
- Related gene:
ENSG00000183421,
- Related loop:
chr21:39975000-40000000~~chr21:40450000-40475000,
chr21:40300000-40325000~~chr21:40450000-40475000,
chr21:40450000-40475000~~chr21:40550000-40575000,
chr21:40450000-40475000~~chr21:40625000-40650000,
chr21:40450000-40475000~~chr21:40675000-40700000,
chr21:40450000-40475000~~chr21:40775000-40800000,
chr21:40450000-40475000~~chr21:40800000-40825000,
chr21:40450000-40475000~~chr21:40825000-40850000,
chr21:40450000-40475000~~chr21:40850000-40875000,
chr21:40450000-40475000~~chr21:40925000-40950000,
chr21:40450000-40475000~~chr21:41025000-41050000,
chr21:40450000-40475000~~chr21:41050000-41075000,
chr21:40450000-40475000~~chr21:41075000-41100000,
chr21:40450000-40475000~~chr21:41125000-41150000,
chr21:40450000-40475000~~chr21:41750000-41775000,
chr21:40465557-40467899~~chr21:40840912-40842965,
chr21:40465557-40467899~~chr21:41068145-41070397,
chr21:40465667-40468011~~chr21:40840995-40843250,
chr21:40465667-40468011~~chr21:41068097-41070414,
chr21:40465872-40468080~~chr21:40840988-40842938,
chr21:40465872-40468080~~chr21:41044806-41046966,
chr21:40466129-40468033~~chr21:40841024-40843128,
chr21:40466131-40467839~~chr21:40840989-40842899,
chr21:40466218-40467881~~chr21:40841049-40843350,
chr21:40466218-40467881~~chr21:41068068-41070387,
chr21:40466231-40468047~~chr21:40511598-40513386,
chr21:40466299-40467874~~chr21:41068067-41070302,
chr21:40466465-40467826~~chr21:40840980-40842929,
chr21:40466473-40467959~~chr21:41068059-41070218,
chr21:40466509-40467846~~chr21:41068098-41070028,