- Basic information
- CohesinDB ID: CDBP00419769
- Locus: chr21-40507529-40508704
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Data sourse: GSE206145-GSE177045, ENCSR230ZWH, GSE72082, ENCSR501LQA, GSE25021, ENCSR330ELC, GSE165895, ENCSR917QNE, GSE67783, GSE76893, ENCSR703TNG, ENCSR199XBQ, ENCSR895JMI, ENCSR193NSH, ENCSR247LSH, ENCSR620NWG, ENCSR767DFK, ENCSR495WGO, ENCSR217ELF, ENCSR000BTQ, ENCSR853VWZ, ENCSR676MJK, ENCSR335RKQ, ENCSR748MVX
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Cell type: MCF-7, Hep-G2, A-549, Liver, HSPC, HFFc6
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 8% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.933
- Subunit: NIPBL,SA1,Rad21,SMC1,Mau2,SMC3
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CTCF binding site: non-CTCF
CTCF motif: False
- Genomic location: TSS,TES,Intragenic
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: Hub
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Hi-C loops: False
Hi-ChIP loops: True
ChIA-PET loops: True
- Compartment:
36% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): False
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Chromatin annotation:
"15_Quies": 80%,
"9_Het": 6%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: MBD3, FOXO1, FOSL1, PGR, HMG20A, SOX2, FOXA1, RXRB, ATF3, NFIC, SMARCE1, TEAD1, KLF6, RCOR2, ZNF217, HNF1B, ESR1, JUN, TCF12, BAF155, EP300, SOX5, DPF2, E2F1, TEAD4, FOXA3, GATAD2A, PDX1, TFAP2C, MLX, MYCN, TOP2A, GATAD1, SAP130, ARID3A, HNF4G, ERG, CHD4, SMARCC2, ETS1, MYC, ONECUT1, HOMEZ, RAD21, GRHL3, RXRA, NKX2-1, GABPA, STAT3, XRCC5, ZNF614, NKX3-1, MIER3, RCOR1, NR2F6, NR3C1, CEBPB, ESRRA, CREB1, TBL1XR1, GRHL2, ZNF652, EBF3, GABPB1, ZHX2, MIXL1, TFE3, ZSCAN2, IRF1, HDAC2, GATA2, ZNF644, GATAD2B, DRAP1, ZGPAT, SMARCA5, NFIL3, ETV5, RUNX1, THAP11, CBX1, BCL6, CEBPA, NKX2-2, SIN3A, SOX13, SMAD3, SMARCC1, ZXDC, CREBBP, RARA, PBX4, ARNT, DAXX, SOX11, NFIB, FOXM1, PBX3, MAFB, FOS, CDK8, ZEB1, TEAD3, NR1H2, MAFK, SP1, NIPBL, BCL11A, HNF4A, REST, ATF7, ASH2L, MBD2, FOXP1, STAG1, PPARG, FOXA2, CREM, MIER2, MAFF, TCF7, HOXB13, KDM1A, YY1, RELA, NEUROD1, JUNB, KAT2B, HIF1A, GATA3, MAX, MTA1, HAND2, KLF4, CEBPG, NCOA3, NR2F2, TP53, PKNOX1, ZNF334, PHOX2B, ELF3, KAT8, NFKBIZ, AR, YAP1, JUND, CUX1, AHR, FOSL2
- Target gene symbol (double-evidenced CRMs): .
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 3
- Number of somatic mutations (non-coding): 3
- Related genes and loops