- Basic information
- CohesinDB ID: CDBP00419771
- Locus: chr21-40511695-40514190
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Data sourse: ENCSR000BLD, GSE206145-GSE177045, ENCSR230ZWH, GSE72082, ENCSR000BLY, GSE105028, GSE121355, GSE103477, GSE111537, GSE131606, GSE108869, ENCSR000EDW, GSE25021, ENCSR000BUC, ENCSR917QNE, GSE115602, ENCSR000BTU, GSE143937, GSE67783, ENCSR000BKV, GSE86191, GSE138405, GSE206145-NatGen2015, GSE112028, GSE130135, ENCSR703TNG, GSE116344, GSE145327, ENCSR000EEG, ENCSR193NSH, ENCSR000BLS, GSE206145, ENCSR000ECE, ENCSR000EHX, ENCSR495WGO, GSE97394, ENCSR217ELF, ENCSR000BTQ, ENCSR167MTG, ENCSR853VWZ, ENCSR956LGB, GSE110061, GSE129526, GSE111913, ENCSR054FKH, GSE68388, GSE83726, GSE126990, GSE50893, GSE131577
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Cell type: MDM, RH4, GM2610, Liver, HuCC-T1, H9-hESC, GM2630, Fibroblast, Ishikawa, HeLa-S3, K-562, DKO, H1-hESC, SNYDER, GM12891, SK-N-SH, RT-112, HeLa-Tet-On, GM19193, GM19099, HUES64, MCF-7, Hela-Kyoto, HCT-116, HL-60, HEK293T, Hep-G2, A-549, OCI-AML-3, HSPC
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 23% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.656
- Subunit: SA1,Rad21,SMC1,SA2,SMC3
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CTCF binding site: CTCF
CTCF motif: True
- Genomic location: TSS,TES
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: Hub
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Hi-C loops: False
Hi-ChIP loops: True
ChIA-PET loops: True
- Compartment:
36% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): False
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Chromatin annotation:
"15_Quies": 78%,
"9_Het": 11%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: ZNF283, POU2F2, SMC1A, CBX1, NANOG, CBX3, EBF1, TOP2A, RBPJ, ZNF534, XBP1, ZBTB48, SMAD3, WT1, FOXA1, STAT1, SRF, ZNF770, TRIM22, ZNF18, YY1, RELA, ZXDC, ZBTB2, JUNB, MYC, CDK6, RAD21, PBX4, ARNT, ZNF444, SMC3, STAT3, MAX, FOS, ZNF143, MED1, CEBPB, PDX1, KLF6, NFE2L2, EZH2, TP53, ESR1, OCA2, NFKB1, EBF3, JUN, ELF3, MAFK, CTCF, TCF12, IRF1, HDAC2, E2F6, BRD4, JUND, E2F1, CUX1, MAZ, TEAD4, STAG1, TFAP2C, FOSL2
- Target gene symbol (double-evidenced CRMs): .
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 16
- Number of somatic mutations (non-coding): 14
- Related genes and loops