- Basic information
- CohesinDB ID: CDBP00419773
- Locus: chr21-40517351-40517452
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Data sourse: GSE120943, GSE98367
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Cell type: Monocytes, Macrophage
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 1% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.978
- Subunit: SMC1
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CTCF binding site: non-CTCF
CTCF motif: False
- Genomic location: TSS,TES
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: Hub
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Hi-C loops: False
Hi-ChIP loops: True
ChIA-PET loops: True
- Compartment:
36% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): Enhancer
- Super enhancer (SEdb): False
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Chromatin annotation:
"15_Quies": 83%,
"9_Het": 10%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: RUNX1, PGR, SMC1A, POU2F2, CEBPA, NKX2-2, RBBP5, ZNF263, SOX2, ID3, POU4F2, XBP1, SIN3A, ZSCAN16, STAT1, FOXA1, MEF2C, DDX5, HOXB13, KDM1A, ERG, RELA, CREBBP, YY1, LYL1, ATF3, RFX1, CHD7, RAD21, ARNT, HIF1A, TFDP1, GRHL3, GABPA, MECOM, TAL1, ZNF143, CDK8, MED1, NCOA3, NR2F2, ELF1, KMT2A, TRIM28, MYB, TEAD1, KDM5B, SAP30, ESR1, EZH2, GRHL2, SETDB1, ELF3, SND1, CTCF, SP1, SPI1, EP300, BAF155, NR4A1, AR, NANOG, HDAC2, REST, GATA2, E2F6, TRIM24, FLI1, ASH2L, HSF1, BRD4, SMC3, STAG1, AHR
- Target gene symbol (double-evidenced CRMs): .
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 0
- Number of somatic mutations (non-coding): 0
- Related genes and loops