- Basic information
- CohesinDB ID: CDBP00419796
- Locus: chr21-40615384-40617576
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Data sourse: ENCSR000BTQ, GSE206145-GSE177045, ENCSR230ZWH, GSE67783, GSE72082, GSE86191, GSE132649, ENCSR000BLY, ENCSR404BPV, ENCSR000EHW, GSE101921, GSE105028, GSE206145-NatGen2015, GSE206145, ENCSR198ZYJ, ENCSR000EHX, ENCSR703TNG, GSE25021, ENCSR917QNE
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Cell type: MCF-7, RPE, HMEC, Fibroblast, HCT-116, T-47D, Neurons-H1, SK-N-SH, Liver, HSPC, H9-hESC
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 8% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.878
- Subunit: SA1,Rad21,SMC1,SA2,SMC3
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CTCF binding site: CTCF
CTCF motif: False
- Genomic location: TES
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: Hub
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Hi-C loops: True
Hi-ChIP loops: False
ChIA-PET loops: True
- Compartment:
36% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): Enhancer
- Super enhancer (SEdb): True
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Chromatin annotation:
"15_Quies": 68%,
"9_Het": 14%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: RUNX1, POU2F2, EZH2phosphoT487, MYCN, NKX2-2, ZFX, XBP1, ZBTB48, WT1, STAT1, FOXA1, TET2, YY1, RELA, ASCL1, MYC, SMARCA4, SP140, TCF4, GRHL3, HIF1A, GABPA, MAX, TP63, NRIP1, NCOA3, ESR1, ZNF334, SETDB1, JUN, CTCF, AR, BRD4, NCOA2, STAG1
- Target gene symbol (double-evidenced CRMs): .
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 17
- Number of somatic mutations (non-coding): 17
- Related genes and loops