- Basic information
- CohesinDB ID: CDBP00419804
- Locus: chr21-40641899-40644014
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Data sourse: ENCSR000BTQ, GSE206145-GSE177045, GSE72082, GSE76893, ENCSR703TNG, GSE25021, GSE115602
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Cell type: MCF-7
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 5% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.989
- Subunit: NIPBL,SA1,Rad21,SMC1,Mau2
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CTCF binding site: CTCF
CTCF motif: False
- Genomic location: Intragenic
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: Hub
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Hi-C loops: True
Hi-ChIP loops: False
ChIA-PET loops: True
- Compartment:
36% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): True
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Chromatin annotation:
"15_Quies": 66%,
"9_Het": 27%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: RUNX1, PGR, CBX1, SIN3A, ZFX, TEAD4, FOXA1, HOXB13, HNF4G, ERG, KDM1A, RELA, CREBBP, ZXDC, AHR, MYC, BRG1, GR, RAD21, GRHL3, NFIB, ARNT, NKX2-1, GATA3, SMARCE1, NKX3-1, RCOR1, HAND2, HDAC3, TLE3, NR3C1, CEBPB, NCOA3, NR2F2, TEAD1, PIAS1, EZH2, ZNF217, ESR1, PKNOX1, OCA2, GRHL2, SETDB1, EBF3, TRPS1, JUN, TCF12, BAF155, AR, PAX3-FOXO1, HDAC2, GATA2, ARID1A, YAP1, ASH2L, BRD4, CTBP2, FOXP1, CLOCK, NCOA2, STAG1, TFAP2C
- Target gene symbol (double-evidenced CRMs): .
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 17
- Number of somatic mutations (non-coding): 0
- Related genes and loops