- Basic information
- CohesinDB ID: CDBP00419808
- Locus: chr21-40658152-40661747
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Data sourse: ENCSR000BTQ, GSE206145-GSE177045, GSE72082, GSE165895, GSE76893, ENCSR404BPV, ENCSR198ZYJ, ENCSR703TNG, GSE25021, GSE115602
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Cell type: MCF-7, Neurons-H1, HFFc6
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 6% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.967
- Subunit: SA1,Rad21,SMC1,Mau2,SMC3
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CTCF binding site: CTCF
CTCF motif: False
- Genomic location: Intragenic
- 3D genome
- TAD boundary: non-Boundary
- Chromatin hubs: Hub
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Hi-C loops: True
Hi-ChIP loops: False
ChIA-PET loops: True
- Compartment:
36% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): Enhancer
- Super enhancer (SEdb): True
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Chromatin annotation:
"15_Quies": 75%,
"9_Het": 9%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: RUNX1, FOXA2, NKX2-2, EBF1, POU5F1, FOXA1, HOXB13, ERG, CREBBP, NEUROD1, SMARCA4, OTX2, GATA3, GABPA, MAFB, NRIP1, NKX3-1, ESRRA, ESR1, EP300, AR, GATA2, POU2F3, FLI1, BRD4, FOXP1, PDX1, TFAP2C
- Target gene symbol (double-evidenced CRMs): .
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 34
- Number of somatic mutations (non-coding): 0
- Related genes and loops