- Basic information
- CohesinDB ID: CDBP00419812
- Locus: chr21-40681108-40681549
-
Data sourse: ENCSR000EHW, GSE67783, ENCSR000EHX, ENCSR000BLY
-
Cell type: HSPC, SK-N-SH
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 1% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.978
- Subunit: SMC3,Rad21,SA1
-
CTCF binding site: non-CTCF
CTCF motif: True
- Genomic location: Intragenic
- 3D genome
- TAD boundary: non-Boundary
- Chromatin hubs: Hub
-
Hi-C loops: True
Hi-ChIP loops: True
ChIA-PET loops: True
- Compartment:
36% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): True
-
Chromatin annotation:
"15_Quies": 70%,
"9_Het": 10%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
-
Co-bound Transcriptional factors: RUNX1, TRP47, PGR, FOXA2, MYCN, TBL1X, CHD2, SOX2, ZFX, POU5F1, XBP1, ZNF263, ZBTB48, RUNX1T1, WT1, FOXA1, CTBP1, TET2, NMYC, HOXB13, HNF4G, KDM1A, ERG, RELA, ASCL1, OGG1, TAF15, MYC, SMARCA4, RAD21, SP140, TCF4, HIF1A, GRHL3, CBX3, NKX2-1, GATA3, ATF2, GABPA, PRDM1, STAT3, PBX3, TOP2A, RCOR1, HDAC3, HAND2, NR3C1, ESRRA, CEBPB, PIAS1, EZH2, ESR1, TP53, PITX3, SETDB1, EBF3, PHOX2B, CTCF, TCF12, USF1, BAF155, EP300, AR, PAX8, HDAC2, GATA2, RXR, REST, IRF4, EGLN2, SIX2, MAML3, FLI1, ASH2L, HSF1, HEXIM1, ATF7, ZNF512B, FOXP1, MAZ, AATF, SMC3, STAG1
- Target gene symbol (double-evidenced CRMs): .
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 5
- Number of somatic mutations (non-coding): 0
- Related genes and loops