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Basic information

CohesinDB ID: CDBP00419843

Locus: chr21-40840467-40843808

Data sourse: ENCSR000BLD, GSE206145-GSE177045, ENCSR230ZWH, GSE72082, ENCSR501LQA, GSE132649, GSE116868, ENCSR760NPX, GSE25021, ENCSR000BLY, ENCSR404BPV, ENCSR150EFU, GSE105028, GSE111537, GSE131606, ENCSR330ELC, ENCSR000EDW, GSE108869, ENCSR000BUC, ENCSR917QNE, ENCSR000EFJ, ENCSR000BTU, GSE115602, GSE143937, GSE165895, GSE67783, ENCSR000BKV, GSE115250, GSE138405, GSE86191, GSE36578, GSE76893, GSE101921, GSE206145-NatGen2015, GSE120943, ENCSR198ZYJ, GSE112028, GSE130135, ENCSR703TNG, GSE106870, GSE116344, GSE145327, GSE94872, ENCSR895JMI, ENCSR000EEG, ENCSR338DUC, GSE76815, GSE98367, ENCSR193NSH, GSE206145, ENCSR768DOX, ENCSR000BLS, ENCSR000EHW, GSE85526, ENCSR000ECE, ENCSR247LSH, ENCSR807WAC, ENCSR000EHX, ENCSR620NWG, ENCSR635OSG, ENCSR767DFK, ENCSR981FDC, ENCSR495WGO, ENCSR984DZW, GSE97394, ENCSR217ELF, ENCSR000BTQ, ENCSR167MTG, ENCSR853VWZ, ENCSR956LGB, ENCSR944ZCT, ENCSR676MJK, GSE111913, ENCSR335RKQ, ENCSR054FKH, ENCSR537EFT, GSE68388, GSE83726, GSE126990, GSE50893, ENCSR748MVX, GSE38411

Cell type: RH4, CVB-hiPSC, CVI-hiPSC, Liver, TC-32, HuCC-T1, H9-hESC, RPE, HMEC, Fibroblast, HEKn, Ishikawa, HeLa-S3, IMR-90, BCBL-1, K-562, HFFc6, DKO, H1-hESC, Monocytes, MB157, GM2588, HUES9, SK-N-SH, RT-112, HeLa-Tet-On, Macrophage, HUES64, MCF-7, T-47D, Hela-Kyoto, HCT-116, HEK293T, Hep-G2, Neurons-H1, A-549, HUVEC, BGO3, OCI-AML-3, HSPC

DNA Sequence of binding site: UCSC hg38

Cohesin category

Peak occupancy ratio: 37% samples have this site.

Cell specificity (0: conserved, 1: cell type specific): 0.544

Subunit: SA1,Rad21,SMC1,SA2,Mau2,SMC3

CTCF binding site: CTCF CTCF motif: False

Genomic location: TSS,Intragenic

3D genome

TAD boundary: non-Boundary

Chromatin hubs: Hub

Hi-C loops: True Hi-ChIP loops: True ChIA-PET loops: True

Compartment: 37% Hi-C samples shows Compartment A

Cis-regulatory elements

Enhancer (Fantom5): Enhancer

Super enhancer (SEdb): True

Chromatin annotation: "14_ReprPCWk": 31%, "13_ReprPC": 20%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).

Co-bound Transcriptional factors: MBD3, PGR, SOX2, XBP1, PATZ1, FOXA1, RING1B, MLL4, ZFHX2, ATF3, PRDM1, ZNF444, CBFB, TP63, MITF, SFPQ, TEAD1, ELF1, TRIM28, RBM39, SNAI2, ZNF217, ESR1, LMO2, OCA2, JUN, CTCF, EP300, BAF155, MNT, GATA6, DPF2, RYBP, E2F6, IRF4, TRIM24, E2F1, ZNF528, TEAD4, GTF2F1, PDX1, TFAP2C, JARID2, POU2F2, NANOG, BRD1, CHD8, MYCN, POU5F1, ZNF263, CTBP1, ZNF317, ZBTB17, DUX4, ZBTB48, ZSCAN21, ZSCAN5A, SRF, ERG2, ERG, ZBTB21, ASCL1, OGG1, ZNF341, MYC, SMARCA4, KDM4A, RAD21, GRHL3, STAT3, XRCC5, NKX3-1, RCOR1, HNRNPH1, CEBPB, ESRRA, HNRNPL, CREB1, EZH2, GRHL2, TRPS1, GABPB1, SPI1, ZNF202, HDAC2, GATA2, GATAD2B, MXD3, FLI1, ZNF777, SMARCA5, NCOA2, PTBP1, RUNX1, CBX1, SMC1A, CEBPA, EZH2phosphoT487, NKX2-2, SIN3A, ZFX, ZNF335, SMAD3, ZNF654, ERG3, CBX8, NMYC, TET2, TRIM22, PRDM10, CREBBP, ZBTB2, ZXDC, OSR2, SP3, ARNT, TFDP1, ZNF48, SMAD4, ETV6, FOS, CHD1, HMGXB4, MED1, ZEB1, TEAD3, PIAS1, SMAD1, TBX5, SETDB1, BCL11A, GSPT2, REST, POU2F3, ASH2L, HNRNPLL, CTBP2, MBD2, FOXP1, BCOR, AATF, SMC3, STAG1, STAG2, ZNF394, TRP47, TBL1X, AGO1, FOXA2, RBBP5, SS18, WT1, CDK9, ZNF580, HOXB13, KDM1A, YY1, RELA, SP140, HIF1A, PCGF1, GATA3, MAX, NRIP1, ZNF143, CEBPG, NCOA3, NR2F2, ZNF791, NR2F1, KDM5B, TP53, PKNOX1, ZNF687, ZSCAN22, EGR2, BRD2, ARRB1, AR, ZNF579, EGLN2, HEXIM1, RB1, HSF1, ZBTB26, NOTCH3, BRD4, JUND, MAZ, ZNF24, AHR, FOSL2

Target gene symbol (double-evidenced CRMs): .

Function elements

Human SNPs: .

Number of somatic mutations (coding): 32

Number of somatic mutations (non-coding): 0

Related genes and loops

Related gene:

eachgene

Deatailed information for cohesin site CDBP00419843