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Basic information

CohesinDB ID: CDBP00419846

Locus: chr21-40848883-40849484

Data sourse: GSE206145-NatGen2015, GSE67783, GSE86191

Cell type: Fibroblast, HCT-116, HSPC

DNA Sequence of binding site: UCSC hg38

Cohesin category

Peak occupancy ratio: 1% samples have this site.

Cell specificity (0: conserved, 1: cell type specific): 0.967

Subunit: SA1,Rad21,SA2

CTCF binding site: CTCF CTCF motif: False

Genomic location: TSS

3D genome

TAD boundary: non-Boundary

Chromatin hubs: Hub

Hi-C loops: True Hi-ChIP loops: True ChIA-PET loops: True

Compartment: 37% Hi-C samples shows Compartment A

Cis-regulatory elements

Enhancer (Fantom5): non-Enhancer

Super enhancer (SEdb): True

Chromatin annotation: "14_ReprPCWk": 48%, "13_ReprPC": 22%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).

Co-bound Transcriptional factors: RUNX1, TRP47, CBFA2T2, CBX1, POU2F2, BRD1, POU5F1, MYCN, ZNF263, ZFX, TEAD4, XBP1, ZBTB48, SMAD3, WT1, FOXA1, ZSCAN5A, TET2, ERG3, ERG, YY1, RELA, KDM1A, OGG1, MYC, RAD21, SP140, ARNT, HIF1A, GRHL3, PRDM9, STAT3, MAX, TP63, ZNF143, MITF, MED1, SCRT2, NR2F1, EZH2, ESR1, SETDB1, CTCF, USF1, SPI1, RXR, E2F6, MXD3, FLI1, HSF1, SCRT1, CLOCK, AATF, SMC3, STAG1, AHR

Target gene symbol (double-evidenced CRMs): .

Function elements

Human SNPs: .

Number of somatic mutations (coding): 0

Number of somatic mutations (non-coding): 3

Related genes and loops

Related gene:

eachgene

Deatailed information for cohesin site CDBP00419846