- Basic information
- CohesinDB ID: CDBP00419848
- Locus: chr21-40851356-40852069
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Data sourse: GSE25021, GSE206145-GSE177045
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Cell type: MCF-7
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 0% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.989
- Subunit: SA1,Rad21
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CTCF binding site: non-CTCF
CTCF motif: False
- Genomic location: TSS
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: Hub
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Hi-C loops: True
Hi-ChIP loops: True
ChIA-PET loops: True
- Compartment:
37% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): False
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Chromatin annotation:
"15_Quies": 46%,
"14_ReprPCWk": 39%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: PGR, XBP1, FOXA1, ZNF444, ATF4, ZSCAN4, JMJD1C, TEAD1, BCLAF1, ESR1, OCA2, CTCF, JUN, BAF155, ZNF512B, E2F1, TFAP2C, POU2F2, POU5F1, MYCN, CTBP1, ZBTB48, ZSCAN5A, NONO, DDX5, ERG, ZBTB21, OGG1, MYC, RAD21, GRHL3, RXRA, ZNF8, STAT3, NR3C1, CEBPB, KMT2A, CREB1, EZH2, GRHL2, ZNF652, SPI1, HDAC2, GATAD2B, ZNF777, RUNX1, CTNNB1, SMC1A, CBX1, HDAC1, EZH2phosphoT487, CEBPA, SIRT6, ZFX, TET2, CREBBP, ZNF384, TAF15, ARNT, NFIB, ATF2, PRDM9, ZNF48, SETDB1, USF1, ATF7, ASH2L, AATF, SMC3, STAG1, TRP47, FOXA2, WT1, ZNF662, ZKSCAN1, KDM1A, YY1, RELA, TARDBP, SP140, HIF1A, GATA3, TAL1, MAX, NRIP1, ZNF143, PLAG1, TLE3, KLF4, NCOA3, TCF7L2, ZNF791, NR2F1, ZNF687, AR, RXR, HSF1, BRD4, MAZ, AHR
- Target gene symbol (double-evidenced CRMs): .
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 0
- Number of somatic mutations (non-coding): 2
- Related genes and loops
- Related gene:
- Related loop:
chr21:40125000-40150000~~chr21:40825000-40850000,
chr21:40150000-40175000~~chr21:40825000-40850000,
chr21:40450000-40475000~~chr21:40825000-40850000,
chr21:40450000-40475000~~chr21:40850000-40875000,
chr21:40475000-40500000~~chr21:40825000-40850000,
chr21:40525000-40550000~~chr21:40825000-40850000,
chr21:40575000-40600000~~chr21:40825000-40850000,
chr21:40700000-40725000~~chr21:40825000-40850000,
chr21:40825000-40850000~~chr21:41025000-41050000,
chr21:40825000-40850000~~chr21:41050000-41075000,
chr21:40846553-40848837~~chr21:41044731-41046662,
chr21:40846553-40848837~~chr21:41068042-41070202,
chr21:40846588-40848800~~chr21:41044806-41046966,
chr21:40846588-40848800~~chr21:41068046-41070192,
chr21:40850000-40875000~~chr21:40950000-40975000,
chr21:40850000-40875000~~chr21:41025000-41050000,
chr21:40850000-40875000~~chr21:41050000-41075000,
chr21:40850000-40875000~~chr21:41075000-41100000,