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Basic information

CohesinDB ID: CDBP00419849

Locus: chr21-40852495-40853087

Data sourse: ENCSR000BLD, ENCSR000BTQ, GSE206145-GSE177045, ENCSR230ZWH, GSE72082, GSE98367, GSE25021, GSE76893, GSE105028, ENCSR000ECE, GSE68388, ENCSR703TNG, GSE106870, GSE97394, GSE115602

Cell type: MCF-7, H1-hESC, Macrophage, CVB-hiPSC, H9-hESC, Liver, HuCC-T1, HUES64

DNA Sequence of binding site: UCSC hg38

Cohesin category

Peak occupancy ratio: 7% samples have this site.

Cell specificity (0: conserved, 1: cell type specific): 0.911

Subunit: SA1,Rad21,SMC1

CTCF binding site: CTCF CTCF motif: True

Genomic location: Intergenic

3D genome

TAD boundary: Boundary

Chromatin hubs: Hub

Hi-C loops: True Hi-ChIP loops: True ChIA-PET loops: True

Compartment: 37% Hi-C samples shows Compartment A

Cis-regulatory elements

Enhancer (Fantom5): non-Enhancer

Super enhancer (SEdb): False

Chromatin annotation: "15_Quies": 55%, "14_ReprPCWk": 31%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).

Co-bound Transcriptional factors: PGR, XBP1, FOXA1, ZNF444, ATF4, ZSCAN4, JMJD1C, TEAD1, BCLAF1, ESR1, OCA2, CTCF, JUN, BAF155, ZNF512B, E2F1, TFAP2C, POU2F2, POU5F1, MYCN, CTBP1, ZBTB48, ZSCAN5A, NONO, DDX5, ERG, ZBTB21, OGG1, MYC, RAD21, GRHL3, RXRA, ZNF8, STAT3, NR3C1, CEBPB, KMT2A, CREB1, EZH2, GRHL2, ZNF652, SPI1, HDAC2, GATAD2B, ZNF777, RUNX1, CTNNB1, SMC1A, CBX1, HDAC1, EZH2phosphoT487, CEBPA, SIRT6, ZFX, TET2, CREBBP, ZNF384, TAF15, ARNT, NFIB, ATF2, PRDM9, ZNF48, SETDB1, USF1, ATF7, ASH2L, AATF, SMC3, STAG1, TRP47, FOXA2, WT1, ZNF662, ZKSCAN1, KDM1A, YY1, RELA, TARDBP, SP140, HIF1A, GATA3, TAL1, MAX, NRIP1, ZNF143, PLAG1, TLE3, KLF4, NCOA3, TCF7L2, ZNF791, NR2F1, ZNF687, AR, RXR, HSF1, BRD4, MAZ, AHR

Target gene symbol (double-evidenced CRMs): .

Function elements

Human SNPs: .

Number of somatic mutations (coding): 0

Number of somatic mutations (non-coding): 4

Related genes and loops

Related gene:

eachgene

Deatailed information for cohesin site CDBP00419849