- Basic information
- CohesinDB ID: CDBP00419854
- Locus: chr21-40886946-40887353
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Data sourse: GSE206145-GSE177045, GSE72082, GSE111913, GSE101921, GSE85526, ENCSR703TNG, GSE25021
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Cell type: MCF-7, HMEC, RT-112, HEKn
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 2% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.956
- Subunit: SA1,Rad21,SMC1,SA2,Mau2
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CTCF binding site: non-CTCF
CTCF motif: False
- Genomic location: Intergenic
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: Hub
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Hi-C loops: True
Hi-ChIP loops: False
ChIA-PET loops: True
- Compartment:
37% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): False
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Chromatin annotation:
"15_Quies": 77%,
"9_Het": 9%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: RUNX1, PGR, CBX1, SMC1A, FOXA2, NKX2-2, CHD8, POU2F2, ZFX, CTBP1, TEAD4, SMAD3, FOXA1, HOXB13, ERG, RELA, CREBBP, JUNB, AHR, MYC, GR, RAD21, ARNT, HIF1A, GABPA, SMARCE1, STAT3, TP63, NRIP1, FOS, ZNF143, RCOR1, MED1, NR3C1, CEBPB, ZNF750, NCOA3, TEAD1, ESRRA, CREB1, SNAI2, PIAS1, STAG1, ETV1, TP53, PKNOX1, ESR1, GRHL2, NFKB1, JUN, BAF155, TFAP2A, AR, DPF2, HDAC2, GATA2, REST, EGLN2, ASH2L, BRD4, FOXP1, NCOA2, STAG2, TFAP2C, FOSL2
- Target gene symbol (double-evidenced CRMs): BACE2
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 0
- Number of somatic mutations (non-coding): 1
- Related genes and loops