- Basic information
- CohesinDB ID: CDBP00419858
- Locus: chr21-40913070-40913480
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Data sourse: GSE120943, GSE86191, GSE98367
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Cell type: HCT-116, Monocytes, Macrophage
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 1% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.967
- Subunit: Rad21,SMC1
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CTCF binding site: CTCF
CTCF motif: False
- Genomic location: Intergenic
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: Hub
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Hi-C loops: True
Hi-ChIP loops: False
ChIA-PET loops: True
- Compartment:
37% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): False
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Chromatin annotation:
"15_Quies": 72%,
"14_ReprPCWk": 19%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
-
Co-bound Transcriptional factors: TOP2A, NME2
- Target gene symbol (double-evidenced CRMs): BACE2
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 0
- Number of somatic mutations (non-coding): 16
- Related genes and loops
- Related gene:
ENSG00000182240,
- Related loop:
chr21:40125000-40150000~~chr21:40900000-40925000,
chr21:40150000-40175000~~chr21:40900000-40925000,
chr21:40175000-40200000~~chr21:40900000-40925000,
chr21:40425000-40450000~~chr21:40900000-40925000,
chr21:40750000-40775000~~chr21:40900000-40925000,
chr21:40800000-40825000~~chr21:40900000-40925000,
chr21:40900000-40925000~~chr21:41000000-41025000,
chr21:40900000-40925000~~chr21:41050000-41075000,
chr21:40900000-40925000~~chr21:41200000-41225000,