- Basic information
- CohesinDB ID: CDBP00419862
- Locus: chr21-40932779-40933193
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Data sourse: GSE206145-NatGen2015, GSE67783
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Cell type: Fibroblast, HSPC
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 1% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.978
- Subunit: SA1,SA2
-
CTCF binding site: CTCF
CTCF motif: False
- Genomic location: Intergenic
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: Hub
-
Hi-C loops: True
Hi-ChIP loops: True
ChIA-PET loops: True
- Compartment:
37% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): False
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Chromatin annotation:
"15_Quies": 82%,
"9_Het": 14%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
-
Co-bound Transcriptional factors: MYCN, KDM4C, ESR1, AATF, TP63
- Target gene symbol (double-evidenced CRMs): MX2,BACE2,B3GALT5
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 0
- Number of somatic mutations (non-coding): 2
- Related genes and loops
- Related gene:
ENSG00000183778,
ENSG00000182240,
ENSG00000183486,
- Related loop:
chr21:39650000-39675000~~chr21:40925000-40950000,
chr21:39975000-40000000~~chr21:40925000-40950000,
chr21:40175000-40200000~~chr21:40925000-40950000,
chr21:40300000-40325000~~chr21:40925000-40950000,
chr21:40450000-40475000~~chr21:40925000-40950000,
chr21:40750000-40775000~~chr21:40925000-40950000,
chr21:40925000-40950000~~chr21:41025000-41050000,
chr21:40925000-40950000~~chr21:41050000-41075000,
chr21:40925000-40950000~~chr21:41075000-41100000,
chr21:40925000-40950000~~chr21:41200000-41225000,
chr21:40925000-40950000~~chr21:41375000-41400000,
chr21:40925000-40950000~~chr21:41650000-41675000,
chr21:40925000-40950000~~chr21:41700000-41725000,