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Basic information

CohesinDB ID: CDBP00419863

Locus: chr21-40936639-40937196

Data sourse: GSE85526, GSE68388

Cell type: HuCC-T1, HEKn

DNA Sequence of binding site: UCSC hg38

Cohesin category

Peak occupancy ratio: 1% samples have this site.

Cell specificity (0: conserved, 1: cell type specific): 0.978

Subunit: SMC1

CTCF binding site: non-CTCF CTCF motif: False

Genomic location: Intergenic

3D genome

TAD boundary: Boundary

Chromatin hubs: Hub

Hi-C loops: True Hi-ChIP loops: True ChIA-PET loops: True

Compartment: 37% Hi-C samples shows Compartment A

Cis-regulatory elements

Enhancer (Fantom5): non-Enhancer

Super enhancer (SEdb): False

Chromatin annotation: "15_Quies": 71%, "7_Enh": 13%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).

Co-bound Transcriptional factors: PGR, SMC1A, CHD8, POU5F1, ZFX, ZBTB17, FOXA1, ERG3, ERG, YY1, ZBTB21, RELA, JUNB, MYC, CHD7, SP3, ARNT, HIF1A, GRHL3, STAT3, FOS, ZNF750, NR3C1, NCOA3, TEAD1, TRIM28, SNAI2, ESR1, OCA2, NFKB1, JUN, BRD2, EHF, AR, PAX3-FOXO1, BRD4, SCRT1, TEAD4, TFAP2C, FOSL2

Target gene symbol (double-evidenced CRMs): MX2,BACE2,B3GALT5

Function elements

Human SNPs: .

Number of somatic mutations (coding): 0

Number of somatic mutations (non-coding): 2

Related genes and loops

Related gene: ENSG00000183778, ENSG00000182240, ENSG00000183486,

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Deatailed information for cohesin site CDBP00419863