- Basic information
- CohesinDB ID: CDBP00419875
- Locus: chr21-41010992-41011299
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Data sourse: GSE206145-GSE177045, GSE67783
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Cell type: MCF-7, HSPC
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 0% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.978
- Subunit: Mau2,SA1
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CTCF binding site: CTCF
CTCF motif: False
- Genomic location: TES
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: Hub
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Hi-C loops: True
Hi-ChIP loops: False
ChIA-PET loops: True
- Compartment:
67% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): True
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Chromatin annotation:
"15_Quies": 60%,
"14_ReprPCWk": 24%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: TRIM25, LCORL, SOX2, XBP1, FOXA1, SUZ12, ZFHX2, ZBTB7B, HDGF, ATF3, BMI1, ZBTB5, ZNF444, TP63, ZSCAN4, BCLAF1, ESR1, OCA2, CTCF, JUN, TCF12, E4F1, MNT, PAX8, SOX6, ZNF512B, E2F1, PLRG1, EHMT2, EED, YBX1, NANOG, CHD8, MYCN, ZNF263, POU5F1, KDM4C, CTBP1, ZBTB1, ZBTB48, DUX4, NONO, DDX5, NBN, ERG2, ERG, OGG1, MYC, RFX1, GRHL3, FOXK2, STAT3, ZNF8, PRDM14, IKZF1, HNRNPH1, NFRKB, ESRRA, CREB1, EZH2, SPI1, HES1, IRF1, SSRP1, GATAD2B, RUNX1, SMC1A, EZH2phosphoT487, CRY1, ZFX, TET2, ERG3, MCM2, TRIM22, CREBBP, ARNT, NFIB, ZNF48, CBFA2T3, ZEB1, KDM6B, NCOA1, SETDB1, SP1, ATF7, HNRNPLL, FOXP1, AATF, SMC3, NCOR2, STAG1, MLLT1, TRP47, TBL1X, ZNF207, MTA3, FOXA2, WT1, ZNF662, ZBTB33, HOXB13, ZKSCAN1, YY1, RELA, TARDBP, MCM3, SP140, HIF1A, ZNF311, MAF1, ZNF143, ZNF592, NCOA3, ZNF544, ZNF791, ZNF687, PKNOX1, IRF5, EGR2, PHOX2B, AR, ZBTB40, RXR, HSF1, NOTCH3, BRD4, MAZ
- Target gene symbol (double-evidenced CRMs): B3GALT5,MX1
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 0
- Number of somatic mutations (non-coding): 6
- Related genes and loops
- Related gene:
ENSG00000183778,
ENSG00000157601,
- Related loop:
chr21:39600000-39625000~~chr21:41000000-41025000,
chr21:40125000-40150000~~chr21:41000000-41025000,
chr21:40150000-40175000~~chr21:41000000-41025000,
chr21:40325000-40350000~~chr21:41000000-41025000,
chr21:40425000-40450000~~chr21:41000000-41025000,
chr21:40475000-40500000~~chr21:41000000-41025000,
chr21:40600000-40625000~~chr21:41000000-41025000,
chr21:40650000-40675000~~chr21:41000000-41025000,
chr21:40800000-40825000~~chr21:41000000-41025000,
chr21:40841049-40843350~~chr21:41006848-41008091,
chr21:40875000-40900000~~chr21:41000000-41025000,
chr21:40900000-40925000~~chr21:41000000-41025000,
chr21:41000000-41025000~~chr21:41425000-41450000,
chr21:41000000-41025000~~chr21:43350000-43375000,