Browse_each

Basic information

CohesinDB ID: CDBP00419876

Locus: chr21-41012053-41012703

Data sourse: GSE86191, GSE120943, GSE68388, GSE98367

Cell type: Macrophage, HCT-116, Monocytes, HuCC-T1

DNA Sequence of binding site: UCSC hg38

Cohesin category

Peak occupancy ratio: 1% samples have this site.

Cell specificity (0: conserved, 1: cell type specific): 0.956

Subunit: Rad21,SMC1

CTCF binding site: CTCF CTCF motif: False

Genomic location: TES,Intragenic

3D genome

TAD boundary: Boundary

Chromatin hubs: Hub

Hi-C loops: True Hi-ChIP loops: False ChIA-PET loops: False

Compartment: 67% Hi-C samples shows Compartment A

Cis-regulatory elements

Enhancer (Fantom5): non-Enhancer

Super enhancer (SEdb): True

Chromatin annotation: "15_Quies": 58%, "14_ReprPCWk": 23%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).

Co-bound Transcriptional factors: TRIM25, LCORL, SOX2, XBP1, FOXA1, SUZ12, ZFHX2, ZBTB7B, HDGF, ATF3, BMI1, ZBTB5, ZNF444, TP63, ZSCAN4, BCLAF1, ESR1, OCA2, CTCF, JUN, TCF12, E4F1, MNT, PAX8, SOX6, ZNF512B, E2F1, PLRG1, EHMT2, EED, YBX1, NANOG, CHD8, MYCN, ZNF263, POU5F1, KDM4C, CTBP1, ZBTB1, ZBTB48, DUX4, NONO, DDX5, NBN, ERG2, ERG, OGG1, MYC, RFX1, GRHL3, FOXK2, STAT3, ZNF8, PRDM14, IKZF1, HNRNPH1, NFRKB, ESRRA, CREB1, EZH2, SPI1, HES1, IRF1, SSRP1, GATAD2B, RUNX1, SMC1A, EZH2phosphoT487, CRY1, ZFX, TET2, ERG3, MCM2, TRIM22, CREBBP, ARNT, NFIB, ZNF48, CBFA2T3, ZEB1, KDM6B, NCOA1, SETDB1, SP1, ATF7, HNRNPLL, FOXP1, AATF, SMC3, NCOR2, STAG1, MLLT1, TRP47, TBL1X, ZNF207, MTA3, FOXA2, WT1, ZNF662, ZBTB33, HOXB13, ZKSCAN1, YY1, RELA, TARDBP, MCM3, SP140, HIF1A, ZNF311, MAF1, ZNF143, ZNF592, NCOA3, ZNF544, ZNF791, ZNF687, PKNOX1, IRF5, EGR2, PHOX2B, AR, ZBTB40, RXR, HSF1, NOTCH3, BRD4, MAZ

Target gene symbol (double-evidenced CRMs): MX1,B3GALT5

Function elements

Human SNPs: .

Number of somatic mutations (coding): 0

Number of somatic mutations (non-coding): 3

Related genes and loops

Related gene: ENSG00000183778, ENSG00000157601,

eachgene

Deatailed information for cohesin site CDBP00419876