- Basic information
- CohesinDB ID: CDBP00419877
- Locus: chr21-41016650-41016843
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Data sourse: ENCSR703TNG, GSE206145-GSE177045
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Cell type: MCF-7
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 0% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.989
- Subunit: Mau2,Rad21
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CTCF binding site: non-CTCF
CTCF motif: False
- Genomic location: Intragenic
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: Hub
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Hi-C loops: True
Hi-ChIP loops: False
ChIA-PET loops: True
- Compartment:
67% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): True
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Chromatin annotation:
"15_Quies": 74%,
"14_ReprPCWk": 19%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: SOX2, ZFX, FOXA1, CREBBP, ASCL1, CDK6, SMARCA4, GRHL3, GATA3, GATA1, ESR1, PKNOX1, NCOA1, GRHL2, ZNF334, NFKB1, SPI1, AR, GATA2, AHR, FOSL2
- Target gene symbol (double-evidenced CRMs): MX1,B3GALT5
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 0
- Number of somatic mutations (non-coding): 4
- Related genes and loops
- Related gene:
ENSG00000183778,
ENSG00000157601,
- Related loop:
chr21:39600000-39625000~~chr21:41000000-41025000,
chr21:40125000-40150000~~chr21:41000000-41025000,
chr21:40150000-40175000~~chr21:41000000-41025000,
chr21:40325000-40350000~~chr21:41000000-41025000,
chr21:40425000-40450000~~chr21:41000000-41025000,
chr21:40475000-40500000~~chr21:41000000-41025000,
chr21:40600000-40625000~~chr21:41000000-41025000,
chr21:40650000-40675000~~chr21:41000000-41025000,
chr21:40800000-40825000~~chr21:41000000-41025000,
chr21:40875000-40900000~~chr21:41000000-41025000,
chr21:40900000-40925000~~chr21:41000000-41025000,
chr21:41000000-41025000~~chr21:41425000-41450000,
chr21:41000000-41025000~~chr21:43350000-43375000,