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Basic information

CohesinDB ID: CDBP00419881

Locus: chr21-41028488-41030425

Data sourse: ENCSR000BTQ, GSE206145-GSE177045, GSE72082, ENCSR703TNG, GSE25021, GSE115602

Cell type: MCF-7

DNA Sequence of binding site: UCSC hg38

Cohesin category

Peak occupancy ratio: 4% samples have this site.

Cell specificity (0: conserved, 1: cell type specific): 0.989

Subunit: Mau2,SA1,Rad21,SMC1

CTCF binding site: non-CTCF CTCF motif: False

Genomic location: Intragenic

3D genome

TAD boundary: Boundary

Chromatin hubs: Hub

Hi-C loops: True Hi-ChIP loops: True ChIA-PET loops: True

Compartment: 67% Hi-C samples shows Compartment A

Cis-regulatory elements

Enhancer (Fantom5): non-Enhancer

Super enhancer (SEdb): False

Chromatin annotation: "15_Quies": 69%, "14_ReprPCWk": 22%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).

Co-bound Transcriptional factors: RUNX1, PGR, CBX1, CEBPA, EZH2phosphoT487, FOXA2, NKX2-2, SOX13, SIN3A, CTBP1, POU4F2, TEAD4, FOXA1, HOXB13, SMARCC1, ERG, RELA, CREBBP, ZXDC, RARA, AHR, ATF3, BRG1, GR, RAD21, GRHL3, HIF1A, ARNT, GATA3, GABPA, SMARCE1, MAX, NRIP1, NKX3-1, ZNF143, FOS, TLE3, NR3C1, CEBPB, ESRRA, PDX1, NR2F2, TEAD1, PIAS1, NR2F1, EZH2, ZNF217, ESR1, KDM5B, GRHL2, SETDB1, TRPS1, TCF12, ZHX2, BAF155, TFAP2A, EP300, SP1, AR, ZNF257, PAX3-FOXO1, DPF2, HDAC2, GATA2, ARID1A, HNF4A, ASH2L, BRD4, CTBP2, JUND, FOXP1, NCOA2, FOXA3, GATAD2A, STAG1, TFAP2C

Target gene symbol (double-evidenced CRMs): .

Function elements

Human SNPs: .

Number of somatic mutations (coding): 0

Number of somatic mutations (non-coding): 5

Related genes and loops

Related gene:

eachgene

Deatailed information for cohesin site CDBP00419881