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Basic information

CohesinDB ID: CDBP00419887

Locus: chr21-41042415-41044725

Data sourse: ENCSR000BLD, GSE206145-GSE177045, ENCSR230ZWH, GSE72082, ENCSR000BLY, GSE105028, GSE103477, GSE131606, GSE25021, ENCSR000EDW, GSE115602, ENCSR917QNE, GSE67783, GSE86191, GSE138405, GSE76893, GSE206145-NatGen2015, GSE138105, ENCSR703TNG, ENCSR000BLS, ENCSR000EHW, GSE85526, ENCSR000ECE, ENCSR000EHX, GSE97394, ENCSR000BTQ, ENCSR167MTG, GSE110061, GSE129526, ENCSR054FKH, GSE68388, GSE126990, ENCSR000ECS

Cell type: MCF-7, H1-hESC, MDM, Fibroblast, HCT-116, Hela-Kyoto, HEKn, Hep-G2, SLK, A-549, DKO, HeLa-S3, HUES64, SK-N-SH, Liver, HSPC, HuCC-T1, H9-hESC

DNA Sequence of binding site: UCSC hg38

Cohesin category

Peak occupancy ratio: 12% samples have this site.

Cell specificity (0: conserved, 1: cell type specific): 0.800

Subunit: SA1,Rad21,SMC1,SA2,SMC3

CTCF binding site: CTCF CTCF motif: True

Genomic location: Intergenic

3D genome

TAD boundary: Boundary

Chromatin hubs: Hub

Hi-C loops: True Hi-ChIP loops: True ChIA-PET loops: True

Compartment: 67% Hi-C samples shows Compartment A

Cis-regulatory elements

Enhancer (Fantom5): non-Enhancer

Super enhancer (SEdb): True

Chromatin annotation: "15_Quies": 66%, "14_ReprPCWk": 26%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).

Co-bound Transcriptional factors: CBX1, SMC1A, STAT1, TRIM22, KDM1A, MYC, RAD21, ZNF444, ZNF143, RCOR1, NFE2, ZMYM3, SMAD1, ESR1, CTCF, BCL11A, ZNF664, ZNF644, RBM25, IRF4, SMC3, ZNF92, STAG1

Target gene symbol (double-evidenced CRMs): .

Function elements

Human SNPs: .

Number of somatic mutations (coding): 0

Number of somatic mutations (non-coding): 28

Related genes and loops

Related gene:

eachgene

Deatailed information for cohesin site CDBP00419887