- Basic information
- CohesinDB ID: CDBP00419889
- Locus: chr21-41055693-41056410
-
Data sourse: GSE206145-GSE177045, GSE120943, GSE67783, GSE98367
-
Cell type: MCF-7, Monocytes, HSPC, Macrophage
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 1% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.956
- Subunit: Mau2,SA1,SMC1
-
CTCF binding site: CTCF
CTCF motif: False
- Genomic location: Intergenic
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: Hub
-
Hi-C loops: True
Hi-ChIP loops: True
ChIA-PET loops: True
- Compartment:
67% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): True
-
Chromatin annotation:
"15_Quies": 68%,
"14_ReprPCWk": 22%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
-
Co-bound Transcriptional factors: CBFA2T2, PGR, ZSCAN5D, EZH2phosphoT487, MYCN, RUNX1T1, ZNF263, ZFX, WT1, ZBTB48, FOXA1, HOXB13, ERG, YY1, RELA, JUNB, AHR, MYC, SP140, GATA3, SMC3, STAT3, ZSCAN4, TP63, FOS, MITF, HAND2, EZH2, ESR1, PHOX2B, CTCF, AR, GATA6, ZBTB40, REST, HSF1, BRD4, MAZ, TEAD4, STAG1, TFAP2C
- Target gene symbol (double-evidenced CRMs): .
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 0
- Number of somatic mutations (non-coding): 3
- Related genes and loops
- Related gene:
- Related loop:
chr21:40125000-40150000~~chr21:41050000-41075000,
chr21:40150000-40175000~~chr21:41050000-41075000,
chr21:40450000-40475000~~chr21:41050000-41075000,
chr21:40525000-40550000~~chr21:41050000-41075000,
chr21:40575000-40600000~~chr21:41050000-41075000,
chr21:40700000-40725000~~chr21:41050000-41075000,
chr21:40725000-40750000~~chr21:41050000-41075000,
chr21:40825000-40850000~~chr21:41050000-41075000,
chr21:40850000-40875000~~chr21:41050000-41075000,
chr21:40900000-40925000~~chr21:41050000-41075000,
chr21:40925000-40950000~~chr21:41050000-41075000,