- Basic information
- CohesinDB ID: CDBP00419894
- Locus: chr21-41089578-41089986
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Data sourse: ENCSR000BLD, GSE72082, GSE86191, GSE105028, GSE25021, GSE97394
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Cell type: MCF-7, H1-hESC, HCT-116, H9-hESC, HUES64
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 2% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.944
- Subunit: SA1,Rad21
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CTCF binding site: CTCF
CTCF motif: False
- Genomic location: Intergenic
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: Hub
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Hi-C loops: True
Hi-ChIP loops: True
ChIA-PET loops: True
- Compartment:
67% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): False
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Chromatin annotation:
"15_Quies": 59%,
"14_ReprPCWk": 35%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: FOXA2, ZFX, STAT1, ERG3, JUNB, MYC, RAD21, GABPA, STAT3, FOS, ZNF736, CEBPB, CREB1, EZH2, NFKB1, JUN, CTCF, INTS13, SCRT1, NCOR2, STAG1, TFAP2C
- Target gene symbol (double-evidenced CRMs): B3GALT5,GET1-SH3BGR,SH3BGR,BACE2
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 0
- Number of somatic mutations (non-coding): 2
- Related genes and loops
- Related gene:
ENSG00000285815,
ENSG00000185437,
ENSG00000183778,
ENSG00000182240,
- Related loop:
chr21:39500000-39525000~~chr21:41075000-41100000,
chr21:39600000-39625000~~chr21:41075000-41100000,
chr21:40125000-40150000~~chr21:41075000-41100000,
chr21:40150000-40175000~~chr21:41075000-41100000,
chr21:40175000-40200000~~chr21:41075000-41100000,
chr21:40425000-40450000~~chr21:41075000-41100000,
chr21:40450000-40475000~~chr21:41075000-41100000,
chr21:40475000-40500000~~chr21:41075000-41100000,
chr21:40625000-40650000~~chr21:41075000-41100000,
chr21:40650000-40675000~~chr21:41075000-41100000,
chr21:40775000-40800000~~chr21:41075000-41100000,
chr21:40850000-40875000~~chr21:41075000-41100000,
chr21:40925000-40950000~~chr21:41075000-41100000,
chr21:41075000-41100000~~chr21:41175000-41200000,