Browse_each

Basic information

CohesinDB ID: CDBP00419895

Locus: chr21-41091092-41091871

Data sourse: GSE120943, GSE72082, GSE115250

Cell type: MCF-7, TC-32, Monocytes

DNA Sequence of binding site: UCSC hg38

Cohesin category

Peak occupancy ratio: 1% samples have this site.

Cell specificity (0: conserved, 1: cell type specific): 0.967

Subunit: Rad21,SMC1

CTCF binding site: CTCF CTCF motif: False

Genomic location: Intergenic

3D genome

TAD boundary: Boundary

Chromatin hubs: Hub

Hi-C loops: True Hi-ChIP loops: True ChIA-PET loops: True

Compartment: 67% Hi-C samples shows Compartment A

Cis-regulatory elements

Enhancer (Fantom5): non-Enhancer

Super enhancer (SEdb): False

Chromatin annotation: "15_Quies": 57%, "14_ReprPCWk": 33%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).

Co-bound Transcriptional factors: RUNX1, SMARCA2, ZSCAN5D, POU5F1, ZFX, XBP1, SMARCC1, ERG, CDK6, TAL1, ETV6, XRCC5, NCOA3, ELF1, EZH2, LMO2, CTCF, FLI1, NOTCH3, BRD4, ZNF605, MRTFB

Target gene symbol (double-evidenced CRMs): BACE2,B3GALT5,GET1-SH3BGR,SH3BGR

Function elements

Human SNPs: .

Number of somatic mutations (coding): 0

Number of somatic mutations (non-coding): 4

Related genes and loops

Related gene: ENSG00000285815, ENSG00000185437, ENSG00000183778, ENSG00000182240,

eachgene

Deatailed information for cohesin site CDBP00419895