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Basic information

CohesinDB ID: CDBP00419904

Locus: chr21-41124570-41125247

Data sourse: GSE206145-NatGen2015, GSE206145-GSE177045

Cell type: MCF-7, Fibroblast

DNA Sequence of binding site: UCSC hg38

Cohesin category

Peak occupancy ratio: 0% samples have this site.

Cell specificity (0: conserved, 1: cell type specific): 0.978

Subunit: Rad21

CTCF binding site: non-CTCF CTCF motif: False

Genomic location: Intergenic

3D genome

TAD boundary: Boundary

Chromatin hubs: Hub

Hi-C loops: True Hi-ChIP loops: True ChIA-PET loops: True

Compartment: 67% Hi-C samples shows Compartment A

Cis-regulatory elements

Enhancer (Fantom5): non-Enhancer

Super enhancer (SEdb): False

Chromatin annotation: "15_Quies": 45%, "14_ReprPCWk": 28%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).

Co-bound Transcriptional factors: POU2F2, PGR, CHD8, MYCN, ZFX, POU4F2, XBP1, WT1, ZBTB48, FOXA1, ZNF205, HLF, TET2, SUZ12, ERG, RELA, MYC, SP140, ARNT, GRHL3, HIF1A, GATA3, ZNF519, TP63, ZNF143, PRDM14, ZNF750, NCOA3, TFAP2C, SNAI2, EZH2, ESR1, CTCF, SPI1, AR, GATA2, FLI1, BRD4, MAZ, SMC3, AHR

Target gene symbol (double-evidenced CRMs): TMPRSS2,MX2,MX1,FAM3B

Function elements

Human SNPs: .

Number of somatic mutations (coding): 0

Number of somatic mutations (non-coding): 2

Related genes and loops

Related gene: ENSG00000183844, ENSG00000183486, ENSG00000157601, ENSG00000184012,

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Deatailed information for cohesin site CDBP00419904