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Basic information

CohesinDB ID: CDBP00419906

Locus: chr21-41131071-41131294

Data sourse: GSE206145-NatGen2015, GSE25021

Cell type: MCF-7, Fibroblast

DNA Sequence of binding site: UCSC hg38

Cohesin category

Peak occupancy ratio: 0% samples have this site.

Cell specificity (0: conserved, 1: cell type specific): 0.978

Subunit: SA1,Rad21

CTCF binding site: non-CTCF CTCF motif: False

Genomic location: Intergenic

3D genome

TAD boundary: Boundary

Chromatin hubs: Hub

Hi-C loops: True Hi-ChIP loops: True ChIA-PET loops: True

Compartment: 67% Hi-C samples shows Compartment A

Cis-regulatory elements

Enhancer (Fantom5): non-Enhancer

Super enhancer (SEdb): False

Chromatin annotation: "15_Quies": 57%, "14_ReprPCWk": 36%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).

Co-bound Transcriptional factors: RUNX1, PGR, FOXA2, MYCN, TOP2A, ZFX, NME2, ZBTB48, WT1, DUX4, FOXA1, MAFF, SUZ12, BAHD1, CDK9, RELA, CREBBP, ATF3, PRDM1, GRHL3, ZIC2, HIF1A, ATF4, OTX2, GATA3, BATF, TAL1, STAT3, XRCC5, ZNF143, GATA1, CEBPG, CEBPB, NCOA3, TEAD1, TRIM28, MYB, ZNF544, TFAP2C, TP53, ESR1, OCA2, ZNF334, ELF3, CTCF, MAFK, MNT, AR, GATA2, SIX2, POU2F3, ATF7, SCRT1, SMC3, STAG1, AHR, EED

Target gene symbol (double-evidenced CRMs): FAM3B,MX2,TMPRSS2,MX1

Function elements

Human SNPs: .

Number of somatic mutations (coding): 0

Number of somatic mutations (non-coding): 1

Related genes and loops

Related gene: ENSG00000183844, ENSG00000183486, ENSG00000157601, ENSG00000184012,

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Deatailed information for cohesin site CDBP00419906