- Basic information
- CohesinDB ID: CDBP00419908
- Locus: chr21-41137303-41137741
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Data sourse: GSE206145, GSE67783, GSE86191
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Cell type: RPE, HCT-116, HSPC
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 1% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.967
- Subunit: SA1,Rad21
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CTCF binding site: CTCF
CTCF motif: False
- Genomic location: TES
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: Hub
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Hi-C loops: True
Hi-ChIP loops: True
ChIA-PET loops: True
- Compartment:
67% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): True
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Chromatin annotation:
"15_Quies": 44%,
"14_ReprPCWk": 36%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: RUNX1, MYCN, ZFX, ZBTB48, WT1, ZSCAN5A, FOXA1, TET2, ERG3, ERG2, ZFHX2, ATF3, RUNX2, MYC, SP140, GRHL3, STAT3, MYB, EZH2, ESR1, EGR2, CTCF, AR, GATA2, HEXIM1, MAZ
- Target gene symbol (double-evidenced CRMs): FAM3B,MX1,MX2,TMPRSS2
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 0
- Number of somatic mutations (non-coding): 4
- Related genes and loops
- Related gene:
ENSG00000183844,
ENSG00000183486,
ENSG00000157601,
ENSG00000184012,
- Related loop:
chr21:40125000-40150000~~chr21:41125000-41150000,
chr21:40143203-40144858~~chr21:41133242-41135103,
chr21:40143218-40145094~~chr21:41133240-41135091,
chr21:40143238-40145160~~chr21:41133234-41134735,
chr21:40143267-40144892~~chr21:41133281-41134757,
chr21:40143268-40144900~~chr21:41133210-41134770,
chr21:40143283-40145087~~chr21:41133208-41135081,
chr21:40143286-40144881~~chr21:41133185-41134897,
chr21:40143311-40145530~~chr21:41133270-41135110,
chr21:40143361-40144725~~chr21:41133411-41134824,
chr21:40143375-40144769~~chr21:41133440-41134760,
chr21:40143385-40144715~~chr21:41133301-41134874,
chr21:40143385-40144767~~chr21:41133283-41134768,
chr21:40143388-40144776~~chr21:41133401-41134738,
chr21:40450000-40475000~~chr21:41125000-41150000,
chr21:41121049-41122875~~chr21:41133208-41135081,
chr21:41125000-41150000~~chr21:41350000-41375000,
chr21:41125000-41150000~~chr21:41425000-41450000,
chr21:41125000-41150000~~chr21:41450000-41475000,
chr21:41125000-41150000~~chr21:41575000-41600000,
chr21:41125000-41150000~~chr21:41600000-41625000,
chr21:41125000-41150000~~chr21:41700000-41725000,
chr21:41125000-41150000~~chr21:43600000-43625000,