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Basic information

CohesinDB ID: CDBP00419909

Locus: chr21-41138800-41139026

Data sourse: GSE67783, GSE86191

Cell type: HCT-116, HSPC

DNA Sequence of binding site: UCSC hg38

Cohesin category

Peak occupancy ratio: 0% samples have this site.

Cell specificity (0: conserved, 1: cell type specific): 0.978

Subunit: SA1,Rad21

CTCF binding site: CTCF CTCF motif: False

Genomic location: TES

3D genome

TAD boundary: Boundary

Chromatin hubs: Hub

Hi-C loops: True Hi-ChIP loops: True ChIA-PET loops: True

Compartment: 67% Hi-C samples shows Compartment A

Cis-regulatory elements

Enhancer (Fantom5): non-Enhancer

Super enhancer (SEdb): True

Chromatin annotation: "15_Quies": 45%, "14_ReprPCWk": 37%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).

Co-bound Transcriptional factors: PGR, SMARCA2, NME2, XBP1, FOXA1, SUZ12, MLL4, ZNF596, ZBTB5, CHD7, TP63, TEAD1, ELF1, ETV1, ESR1, OCA2, CTCF, JUN, EP300, E4F1, BAF155, MNT, E2F6, SMC1, TEAD4, PDX1, TFAP2C, GLIS1, POU2F2, CHD8, MYCN, CTBP1, ZBTB48, STAT1, NONO, ERG, ETS1, MCM5, MYC, RAD21, RXRA, GABPA, STAT3, NKX3-1, ARNTL, NR3C1, CEBPB, ESRRA, CREB1, EZH2, GRHL2, ZHX2, SSRP1, GATA2, FLI1, MRTFB, RUNX1, CRY1, ZFX, SMAD3, TET2, CREBBP, RUNX2, ARNT, PBX4, FOS, CDK8, PIAS1, SP1, AATF, STAG1, STAG2, TRP47, SS18, WT1, HOXB13, ZKSCAN1, YY1, RELA, MCM3, SP140, HIF1A, GATA3, TAL1, MAX, NRIP1, GATA1, ZNF143, NCOA3, NR2F2, KDM5B, TP53, PKNOX1, ARRB1, AR, YAP1, EGLN2, HSF1, BRD4, MAZ, ZNF316

Target gene symbol (double-evidenced CRMs): MX2,FAM3B,TMPRSS2,MX1

Function elements

Human SNPs: .

Number of somatic mutations (coding): 0

Number of somatic mutations (non-coding): 0

Related genes and loops

Related gene: ENSG00000183844, ENSG00000183486, ENSG00000157601, ENSG00000184012,

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Deatailed information for cohesin site CDBP00419909