- Basic information
- CohesinDB ID: CDBP00419912
- Locus: chr21-41143510-41144226
-
Data sourse: GSE206145-NatGen2015, GSE67783, GSE86191
-
Cell type: Fibroblast, HCT-116, HSPC
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 1% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.967
- Subunit: SA1,Rad21,SA2
-
CTCF binding site: CTCF
CTCF motif: False
- Genomic location: TSS,TES
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: Hub
-
Hi-C loops: True
Hi-ChIP loops: True
ChIA-PET loops: True
- Compartment:
67% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): True
-
Chromatin annotation:
"14_ReprPCWk": 43%,
"15_Quies": 39%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
-
Co-bound Transcriptional factors: PGR, XBP1, FOXA1, MLL4, ATF3, CTCFL, PRDM1, ZNF444, SMARCE1, TP63, TEAD1, ETV1, SNAI2, LMO2, ESR1, JUN, CTCF, EP300, MNT, DPF2, RFX5, ZNF512B, TEAD4, TFAP2C, POU2F2, CHD8, MYCN, CTBP1, ZBTB48, ZSCAN5A, ERG, ASCL1, MYC, SMARCA4, RAD21, GRHL3, GABPA, STAT3, XRCC5, RCOR1, NFE2, ARNTL, NR3C1, CEBPB, ESRRA, KMT2A, CREB1, ZBTB11, EZH2, GRHL2, ZHX2, SPI1, EHF, HDAC2, SIX2, HCFC1, NCOA2, MYF5, RUNX1, SMC1A, CBX1, NKX2-2, SIN3A, ZFX, AFF4, SMAD3, TET2, CREBBP, RUNX2, PBX4, NFIB, ARNT, NRF1, FOS, MED1, TEAD3, ASH2L, AATF, SMC3, ELL2, NCOR2, STAG1, FOXA2, WT1, ZBTB33, RELA, JUNB, SP140, HIF1A, GATA3, TAL1, MAX, NRIP1, ZNF143, NCOA3, NR2F1, KDM5B, TP53, PKNOX1, NFKB1, MYOD1, ELF3, AR, PAX3-FOXO1, YAP1, EGLN2, HSF1, BRD4, MAZ, AHR
- Target gene symbol (double-evidenced CRMs): MX2,FAM3B,TMPRSS2,MX1
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 0
- Number of somatic mutations (non-coding): 0
- Related genes and loops
- Related gene:
ENSG00000183844,
ENSG00000183486,
ENSG00000157601,
ENSG00000184012,
- Related loop:
chr21:40125000-40150000~~chr21:41125000-41150000,
chr21:40450000-40475000~~chr21:41125000-41150000,
chr21:41125000-41150000~~chr21:41350000-41375000,
chr21:41125000-41150000~~chr21:41425000-41450000,
chr21:41125000-41150000~~chr21:41450000-41475000,
chr21:41125000-41150000~~chr21:41575000-41600000,
chr21:41125000-41150000~~chr21:41600000-41625000,
chr21:41125000-41150000~~chr21:41700000-41725000,
chr21:41125000-41150000~~chr21:43600000-43625000,