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Basic information

CohesinDB ID: CDBP00419915

Locus: chr21-41149841-41150938

Data sourse: GSE67783, ENCSR153HNT, GSE86191

Cell type: K-562, HCT-116, HSPC

DNA Sequence of binding site: UCSC hg38

Cohesin category

Peak occupancy ratio: 1% samples have this site.

Cell specificity (0: conserved, 1: cell type specific): 0.967

Subunit: SA1,Rad21

CTCF binding site: CTCF CTCF motif: False

Genomic location: TSS

3D genome

TAD boundary: Boundary

Chromatin hubs: Hub

Hi-C loops: True Hi-ChIP loops: True ChIA-PET loops: True

Compartment: 67% Hi-C samples shows Compartment A

Cis-regulatory elements

Enhancer (Fantom5): non-Enhancer

Super enhancer (SEdb): True

Chromatin annotation: "14_ReprPCWk": 38%, "15_Quies": 32%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).

Co-bound Transcriptional factors: PGR, LCORL, SOX2, ZNF621, XBP1, FOXA1, SUZ12, HDGF, BMI1, ZBTB5, CHD7, ZNF444, ZNF736, CDC5L, KLF5, ELF1, TRIM28, TEAD1, BCLAF1, LMO2, ESR1, OCA2, JUN, CTCF, TCF12, EP300, E4F1, MNT, ZNF157, GATA6, GLI4, ZNF512B, ZNF776, E2F1, ZNF677, SMC1, TEAD4, ZNF92, GTF2F1, EHMT2, TFAP2C, YBX1, NANOG, POU2F2, ZSCAN5D, ZNF263, MYCN, POU5F1, TOP2A, CTBP1, ZBTB1, ZBTB48, ZSCAN5A, STAT1, NONO, DDX5, ARID3A, MYC, MCM5, RFX1, RAD21, GRHL3, FOXK2, STAT3, APC, ZNF8, PRDM14, ZNF639, ARNTL, NR3C1, ESRRA, CEBPB, CREB1, EZH2, ARHGAP35, SPI1, HES1, EHF, ZNF257, IRF1, HDAC2, GATA2, SSRP1, ZNF644, GATAD2B, RUNX1, CBX1, BCL6, HDAC1, LDB1, SIRT6, AFF4, ZFX, SIN3A, SMAD3, TET2, TRIM22, CREBBP, ZBTB2, RUNX2, SMAD2, GATA4, ARNT, NRF1, SOX11, NFIB, ATF2, PRDM9, PBX3, MED1, SMAD1, NIPBL, BCL11A, HNF4A, ATF7, CTBP2, BCOR, FOXP1, SMC3, ELL2, NCOR2, STAG2, STAG1, MLLT1, ZNF283, CBFA2T2, ZNF207, MTA3, WT1, ZNF662, ZBTB33, CDK9, ZKSCAN1, BCL3, KDM1A, YY1, RELA, TARDBP, NEUROD1, ZNF282, MCM3, SP140, HIF1A, OTX2, GATA3, ZNF311, TAL1, MAX, NRIP1, ZNF143, TLE3, NCOA3, NR2F2, NR2F1, KDM5B, TP53, ZNF687, PKNOX1, ELF3, T, AR, HSF1, BRD4, CLOCK, MAZ, AHR

Target gene symbol (double-evidenced CRMs): TMPRSS2,PRDM15,MX1,MX2,FAM3B

Function elements

Human SNPs: .

Number of somatic mutations (coding): 0

Number of somatic mutations (non-coding): 5

Related genes and loops

Related gene: ENSG00000183844, ENSG00000183486, ENSG00000157601, ENSG00000184012, ENSG00000141956,

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Deatailed information for cohesin site CDBP00419915