- Basic information
- CohesinDB ID: CDBP00419916
- Locus: chr21-41151775-41151894
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Data sourse: GSE120943, GSE98367
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Cell type: Monocytes, Macrophage
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 1% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.978
- Subunit: SMC1
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CTCF binding site: non-CTCF
CTCF motif: False
- Genomic location: TSS
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: Hub
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Hi-C loops: True
Hi-ChIP loops: True
ChIA-PET loops: True
- Compartment:
67% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): False
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Chromatin annotation:
"14_ReprPCWk": 45%,
"15_Quies": 41%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: RELA, RUNX1, CHD8, BCLAF1, GATAD2B, ZNF544, TRIM28, NME2, PRDM1, ARNT, BRD4, TAL1, ZNF776, KDM1A, ZNF662, NFKB1, STAT3, ERG, SPI1, AHR
- Target gene symbol (double-evidenced CRMs): TMPRSS2,FAM3B,PRDM15,MX2,MX1
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 0
- Number of somatic mutations (non-coding): 0
- Related genes and loops
- Related gene:
ENSG00000183844,
ENSG00000183486,
ENSG00000157601,
ENSG00000184012,
ENSG00000141956,
- Related loop:
chr21:40125000-40150000~~chr21:41125000-41150000,
chr21:40450000-40475000~~chr21:41125000-41150000,
chr21:41125000-41150000~~chr21:41350000-41375000,
chr21:41125000-41150000~~chr21:41425000-41450000,
chr21:41125000-41150000~~chr21:41450000-41475000,
chr21:41125000-41150000~~chr21:41575000-41600000,
chr21:41125000-41150000~~chr21:41600000-41625000,
chr21:41125000-41150000~~chr21:41700000-41725000,
chr21:41125000-41150000~~chr21:43600000-43625000,
chr21:41150000-41175000~~chr21:41350000-41375000,
chr21:41150000-41175000~~chr21:41425000-41450000,
chr21:41150000-41175000~~chr21:41450000-41475000,
chr21:41150000-41175000~~chr21:41775000-41800000,