- Basic information
- CohesinDB ID: CDBP00419921
- Locus: chr21-41173473-41173655
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Data sourse: GSE206145, GSE206145-NatGen2015
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Cell type: RPE, Fibroblast
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 1% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.978
- Subunit: NIPBL,SA1,Rad21,SA2
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CTCF binding site: non-CTCF
CTCF motif: False
- Genomic location: TES
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: Hub
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Hi-C loops: True
Hi-ChIP loops: True
ChIA-PET loops: True
- Compartment:
67% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): True
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Chromatin annotation:
"5_TxWk": 39%,
"15_Quies": 35%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: AR, RELA, RUNX1, GATA2, ZSCAN5D, TERF1, NR2F2, CREB1, TRIM28, MCM3, EZH2, XBP1, ZFX, BRD4, ESR1, PBX4, FOXA1, POU5F1, PBX2, TFAP2C
- Target gene symbol (double-evidenced CRMs): MX1,PRDM15,BACE2,FAM3B,TMPRSS2,MX2
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 0
- Number of somatic mutations (non-coding): 0
- Related genes and loops
- Related gene:
ENSG00000182240,
ENSG00000183844,
ENSG00000183486,
ENSG00000157601,
ENSG00000184012,
ENSG00000141956,
- Related loop:
chr21:40875000-40900000~~chr21:41175000-41200000,
chr21:41075000-41100000~~chr21:41175000-41200000,
chr21:41121260-41122868~~chr21:41167149-41169803,
chr21:41150000-41175000~~chr21:41350000-41375000,
chr21:41150000-41175000~~chr21:41425000-41450000,
chr21:41150000-41175000~~chr21:41450000-41475000,
chr21:41150000-41175000~~chr21:41775000-41800000,
chr21:41167149-41169803~~chr21:41235512-41237477,
chr21:41167199-41169386~~chr21:41250553-41252905,
chr21:41169934-41171396~~chr21:41373764-41374984,
chr21:41175000-41200000~~chr21:41275000-41300000,
chr21:41175000-41200000~~chr21:41425000-41450000,
chr21:41175000-41200000~~chr21:41750000-41775000,
chr21:41175000-41200000~~chr21:41775000-41800000,