- Basic information
- CohesinDB ID: CDBP00419922
- Locus: chr21-41177726-41178272
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Data sourse: GSE67783, GSE86191
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Cell type: HCT-116, HSPC
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 1% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.978
- Subunit: SA1,Rad21
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CTCF binding site: CTCF
CTCF motif: False
- Genomic location: TSS,TES
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: Hub
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Hi-C loops: True
Hi-ChIP loops: False
ChIA-PET loops: True
- Compartment:
67% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): True
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Chromatin annotation:
"15_Quies": 39%,
"5_TxWk": 30%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: PGR, CHD8, MYCN, ZFX, WT1, ZBTB48, FOXA1, YY1, RELA, MYC, ARNT, HIF1A, TAL1, PRDM14, PLAG1, TFAP2C, CCAR2, ESR1, CTCF, JUN, SIX2, NCOR1, NOTCH3, ZNF528, MAZ, STAG1, AHR
- Target gene symbol (double-evidenced CRMs): PRDM15,FAM3B,RIPK4,MX1,BACE2
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 3
- Number of somatic mutations (non-coding): 1
- Related genes and loops
- Related gene:
ENSG00000182240,
ENSG00000183844,
ENSG00000157601,
ENSG00000183421,
ENSG00000141956,
- Related loop:
chr21:40875000-40900000~~chr21:41175000-41200000,
chr21:41075000-41100000~~chr21:41175000-41200000,
chr21:41150000-41175000~~chr21:41350000-41375000,
chr21:41150000-41175000~~chr21:41425000-41450000,
chr21:41150000-41175000~~chr21:41450000-41475000,
chr21:41150000-41175000~~chr21:41775000-41800000,
chr21:41175000-41200000~~chr21:41275000-41300000,
chr21:41175000-41200000~~chr21:41425000-41450000,
chr21:41175000-41200000~~chr21:41750000-41775000,
chr21:41175000-41200000~~chr21:41775000-41800000,