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Basic information

CohesinDB ID: CDBP00419931

Locus: chr21-41214800-41215219

Data sourse: GSE67783, GSE86191

Cell type: HCT-116, HSPC

DNA Sequence of binding site: UCSC hg38

Cohesin category

Peak occupancy ratio: 1% samples have this site.

Cell specificity (0: conserved, 1: cell type specific): 0.978

Subunit: SA1,Rad21

CTCF binding site: CTCF CTCF motif: False

Genomic location: Intragenic

3D genome

TAD boundary: Boundary

Chromatin hubs: Hub

Hi-C loops: True Hi-ChIP loops: False ChIA-PET loops: True

Compartment: 67% Hi-C samples shows Compartment A

Cis-regulatory elements

Enhancer (Fantom5): non-Enhancer

Super enhancer (SEdb): True

Chromatin annotation: "15_Quies": 48%, "5_TxWk": 26%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).

Co-bound Transcriptional factors: RUNX1, FOXO1, TRP47, SMC1A, BCL6, ZSCAN5D, MYCN, TBL1X, SIRT6, KDM4C, ZFX, WT1, ZBTB48, FOXA1, TET2, ERG3, ZNF823, ZKSCAN1, KDM1A, YY1, RELA, ERG, ATF3, MCM5, MYC, SP140, NRF1, GRHL3, TAL1, TP63, CHD1, TEAD1, TRIM28, MYB, KDM6B, ZNF3, OCA2, GRHL2, ZNF334, CTCF, JUN, ZNF664, AR, REST, RBM25, HSF1, BRD4, AATF, HCFC1R1, SMC3, NCOR2, STAG1, TFAP2C, EED

Target gene symbol (double-evidenced CRMs): SLC37A1,RIPK4,PDE9A,TMPRSS2,RSPH1,PRDM15,BACE2,MX1,C2CD2,UMODL1

Function elements

Human SNPs: .

Number of somatic mutations (coding): 3

Number of somatic mutations (non-coding): 0

Related genes and loops

Related gene: ENSG00000182240, ENSG00000157601, ENSG00000184012, ENSG00000183421, ENSG00000141956, ENSG00000157617, ENSG00000177398, ENSG00000160188, ENSG00000160190, ENSG00000160191,

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Deatailed information for cohesin site CDBP00419931