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Basic information

CohesinDB ID: CDBP00419933

Locus: chr21-41217596-41218016

Data sourse: ENCSR703TNG, GSE206145-GSE177045, GSE111913, GSE86191

Cell type: MCF-7, RT-112, HCT-116

DNA Sequence of binding site: UCSC hg38

Cohesin category

Peak occupancy ratio: 1% samples have this site.

Cell specificity (0: conserved, 1: cell type specific): 0.967

Subunit: Mau2,SA1,Rad21

CTCF binding site: CTCF CTCF motif: False

Genomic location: Intragenic

3D genome

TAD boundary: Boundary

Chromatin hubs: Hub

Hi-C loops: True Hi-ChIP loops: False ChIA-PET loops: True

Compartment: 67% Hi-C samples shows Compartment A

Cis-regulatory elements

Enhancer (Fantom5): non-Enhancer

Super enhancer (SEdb): True

Chromatin annotation: "15_Quies": 42%, "5_TxWk": 22%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).

Co-bound Transcriptional factors: RUNX1, TRP47, PGR, CBX1, CEBPA, ZNF263, POU5F1, MYCN, FIP1L1, ZFX, ZMYND11, ZBTB48, WT1, FOXA1, TET2, ERG3, ERG2, SP4, MLL4, ZFHX2, YY1, RELA, ATF3, MYC, GATA4, SP140, ARNT, PROX1, GABPA, SP2, NFE2, CEBPG, CEBPB, NR3C1, NCOA3, CEBPD, ZNF573, KLF6, NR2F1, TFAP2C, TCF7L2, TP53, ESR1, GRHL2, ZNF334, EGR2, CTCF, T, JUN, TFAP2A, BHLHE40, AR, MXD3, EGR1, HSF1, ZBTB26, BRD4, JUND, MAZ, ATF1, AHR

Target gene symbol (double-evidenced CRMs): SLC37A1,C2CD2,RIPK4,BACE2,PDE9A,MX1,UMODL1,PRDM15,RSPH1,TMPRSS2

Function elements

Human SNPs: .

Number of somatic mutations (coding): 3

Number of somatic mutations (non-coding): 0

Related genes and loops

Related gene: ENSG00000182240, ENSG00000157601, ENSG00000184012, ENSG00000183421, ENSG00000141956, ENSG00000157617, ENSG00000177398, ENSG00000160188, ENSG00000160190, ENSG00000160191,

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Deatailed information for cohesin site CDBP00419933