- Basic information
- CohesinDB ID: CDBP00419945
- Locus: chr21-41245248-41246129
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Data sourse: GSE67783, GSE86191, GSE138405, GSE111913, GSE206145, GSE25021
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Cell type: MCF-7, RPE, Hela-Kyoto, HCT-116, RT-112, HSPC
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 2% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.933
- Subunit: SA1,Rad21,SA2
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CTCF binding site: CTCF
CTCF motif: False
- Genomic location: Intragenic
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: Hub
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Hi-C loops: False
Hi-ChIP loops: False
ChIA-PET loops: True
- Compartment:
67% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): True
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Chromatin annotation:
"5_TxWk": 39%,
"15_Quies": 32%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: NFIA, TRIM25, PGR, HMG20A, E2F7, SOX2, NME2, XBP1, PATZ1, FOXA1, SUZ12, ZFHX2, INSM2, MORC2, CBFB, MITF, ZNF629, KLF5, TEAD1, TRIM28, SNAI2, ESR1, OCA2, USF2, CTCF, JUN, TCF12, BAF155, KLF1, EP300, GATA6, SOX5, TRIM24, ZNF528, SMC1, TEAD4, FOXA3, GATAD2A, PDX1, TFAP2C, EED, NANOG, CHD8, POU2F2, ZSCAN5D, POU5F1, MYCN, TOP2A, CDK7, BRD3, CTBP1, ZMYND11, ZNF263, ZBTB48, DUX4, STAT1, SAP130, HNF4G, ERG, ZBTB21, OGG1, MYC, EZH1, GRHL3, GABPA, STAT3, XRCC5, NKX3-1, PRDM14, DNMT3B, NR2F6, ZNF639, NR3C1, CEBPB, CREB1, EZH2, KLF8, BMPR1A, FEZF1, GABPB1, ZHX2, TFE3, KLF17, GATA2, MXD3, FLI1, ZGPAT, NFIL3, ZNF554, RUNX1, THAP11, BCL6, CEBPA, LDB1, SOX13, ZFX, SMAD3, TET2, PRDM10, RARA, PRPF4, CREBBP, RUNX2, GATA4, OSR2, NRF1, ARNT, ZBTB10, PRDM9, SMAD4, CBFA2T3, NCAPH2, SP2, SUPT5H, CSNK2A1, ZXDB, MYB, PIAS1, L3MBTL2, SETDB1, MBD1, USF1, SP1, NIPBL, BCL11A, NR4A1, IKZF5, ASH2L, HNRNPLL, FOXP1, AATF, STAG1, STAG2, NELFA, TRP47, CBFA2T2, PPARG, AGO1, FOXA2, CREM, PAF1, ZNF600, ZNF692, WT1, HOXB13, ZNF580, ZKSCAN1, RELA, JUNB, SP140, ZFP36, HIF1A, MAF1, MAX, TAL1, GATA1, TLE3, CEBPG, SP7, NR2F1, KDM5B, EGR2, T, BRD2, ZNF843, ELF3, AR, RXR, RBAK, ZNF366, HEXIM1, HSF1, RNF2, ZBTB26, BRD4, MAZ, AHR
- Target gene symbol (double-evidenced CRMs): BACE2
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 69
- Number of somatic mutations (non-coding): 23
- Related genes and loops