- Basic information
- CohesinDB ID: CDBP00419949
- Locus: chr21-41254834-41255643
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Data sourse: GSE206145, GSE67783, GSE86191
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Cell type: RPE, HCT-116, HSPC
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 1% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.967
- Subunit: SA1,Rad21
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CTCF binding site: CTCF
CTCF motif: False
- Genomic location: Intragenic
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: Hub
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Hi-C loops: False
Hi-ChIP loops: False
ChIA-PET loops: True
- Compartment:
81% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): True
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Chromatin annotation:
"15_Quies": 31%,
"5_TxWk": 24%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: GLIS1, ZNF17, ZSCAN5D, ZNF263, TBL1X, MYCN, ZFX, ZMYND11, SMAD3, ZBTB48, WT1, TET2, HOXC5, RELA, NOTCH1, JUNB, MYC, ZFP64, SP140, DAXX, GRHL3, SOX11, ZNF417, TAL1, MAX, ZNF143, FOS, ZNF320, ZNF736, MED1, ZNF587, NCOA3, TRIM28, ETV1, TP53, OCA2, ESR1, BMPR1A, GRHL2, SETDB1, JUN, TCF12, USF1, SPI1, CTCF, ZNF337, PAX3-FOXO1, RXR, E2F6, E2F4, BRD4, SMC1, ZNF280A, NCOA2, ZNF554, STAG1
- Target gene symbol (double-evidenced CRMs): BACE2
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 12
- Number of somatic mutations (non-coding): 0
- Related genes and loops