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Basic information

CohesinDB ID: CDBP00419957

Locus: chr21-41291671-41292309

Data sourse: GSE67783, GSE86191

Cell type: HCT-116, HSPC

DNA Sequence of binding site: UCSC hg38

Cohesin category

Peak occupancy ratio: 0% samples have this site.

Cell specificity (0: conserved, 1: cell type specific): 0.978

Subunit: SA1,Rad21

CTCF binding site: CTCF CTCF motif: False

Genomic location: Intergenic

3D genome

TAD boundary: Boundary

Chromatin hubs: Hub

Hi-C loops: True Hi-ChIP loops: True ChIA-PET loops: True

Compartment: 81% Hi-C samples shows Compartment A

Cis-regulatory elements

Enhancer (Fantom5): non-Enhancer

Super enhancer (SEdb): False

Chromatin annotation: "14_ReprPCWk": 41%, "13_ReprPC": 24%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).

Co-bound Transcriptional factors: RUNX1, NFYB, TRP47, CHD8, FOXA2, MYCN, POU5F1, ZFX, TEAD4, XBP1, ZBTB48, WT1, ZSCAN5A, SMAD3, FOXA1, TET2, CBX8, ERG2, ETV5, YY1, RELA, ASCL1, OGG1, ATF3, RUNX2, MYC, SP140, GRHL3, ARNT, STAT3, PAX5, TAL1, ZNF143, ZNF736, NCOA3, TRIM28, EZH2, CTCF, GSPT2, AR, PAX8, GATA2, POU2F3, HSF1, RNF2, BRD4, PCGF2, SCRT1, SMC3, ZNF554, STAG1

Target gene symbol (double-evidenced CRMs): RIPK4,UMODL1,BACE2,C2CD2,MX1,TMPRSS2,MX2,PRDM15

Function elements

Human SNPs: .

Number of somatic mutations (coding): 0

Number of somatic mutations (non-coding): 4

Related genes and loops

Related gene: ENSG00000182240, ENSG00000183486, ENSG00000157601, ENSG00000184012, ENSG00000183421, ENSG00000141956, ENSG00000157617, ENSG00000177398,

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Deatailed information for cohesin site CDBP00419957