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Basic information

CohesinDB ID: CDBP00419958

Locus: chr21-41295717-41296311

Data sourse: GSE111913, GSE86191

Cell type: RT-112, HCT-116

DNA Sequence of binding site: UCSC hg38

Cohesin category

Peak occupancy ratio: 1% samples have this site.

Cell specificity (0: conserved, 1: cell type specific): 0.978

Subunit: SA1,Rad21,SA2,SMC1

CTCF binding site: CTCF CTCF motif: False

Genomic location: Intergenic

3D genome

TAD boundary: Boundary

Chromatin hubs: Hub

Hi-C loops: True Hi-ChIP loops: True ChIA-PET loops: True

Compartment: 81% Hi-C samples shows Compartment A

Cis-regulatory elements

Enhancer (Fantom5): non-Enhancer

Super enhancer (SEdb): False

Chromatin annotation: "14_ReprPCWk": 50%, "15_Quies": 36%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).

Co-bound Transcriptional factors: RUNX1, TRP47, PGR, CHD8, MYCN, ZFX, XBP1, DUX4, ZBTB48, WT1, FOXA1, TET2, ERG3, HOXB13, ZKSCAN1, YY1, RELA, PRPF4, MYC, PRDM1, ARNT, HIF1A, SP140, GRHL3, TAL1, TP63, ZNF143, KLF4, NCOA3, KLF5, TEAD1, ELF1, TFAP2C, SNAI2, TP53, OCA2, ESR1, ZNF334, JUN, ZNF436, CTCF, HNF4A, AR, HSF1, RNF2, BRD4, SCRT1, MAZ, SMC3, AHR

Target gene symbol (double-evidenced CRMs): PRDM15,UMODL1,MX1,TMPRSS2,RIPK4,BACE2,MX2,C2CD2

Function elements

Human SNPs: .

Number of somatic mutations (coding): 0

Number of somatic mutations (non-coding): 3

Related genes and loops

Related gene: ENSG00000182240, ENSG00000183486, ENSG00000157601, ENSG00000184012, ENSG00000183421, ENSG00000141956, ENSG00000157617, ENSG00000177398,

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Deatailed information for cohesin site CDBP00419958