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Basic information

CohesinDB ID: CDBP00419960

Locus: chr21-41310090-41310814

Data sourse: ENCSR000BTQ, ENCSR000BTU, ENCSR000EAC, GSE67783, GSE72082, GSE86191, GSE98367, GSE111913, ENCSR054FKH, ENCSR000BMY, GSE103477, ENCSR703TNG, GSE25021, GSE50893, GSE126755

Cell type: MDM, GM2610, GM19240, Ishikawa, GM12890, GM2255, GM18486, SNYDER, GM12878, GM2588, GM19239, RT-112, GM19193, Macrophage, GM19099, MCF-7, GM12892, HCT-116, Hep-G2, GM19238, Neutrophil, HSPC

DNA Sequence of binding site: UCSC hg38

Cohesin category

Peak occupancy ratio: 9% samples have this site.

Cell specificity (0: conserved, 1: cell type specific): 0.756

Subunit: SA1,Rad21,SA2,SMC1

CTCF binding site: CTCF CTCF motif: False

Genomic location: Intragenic

3D genome

TAD boundary: non-Boundary

Chromatin hubs: Hub

Hi-C loops: True Hi-ChIP loops: True ChIA-PET loops: True

Compartment: 81% Hi-C samples shows Compartment A

Cis-regulatory elements

Enhancer (Fantom5): non-Enhancer

Super enhancer (SEdb): False

Chromatin annotation: "14_ReprPCWk": 59%, "15_Quies": 18%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).

Co-bound Transcriptional factors: RUNX1, PGR, SMC1A, BRD1, POU2F2, EZH2phosphoT487, ZNF263, TOP2A, MYCN, ZFX, XBP1, WT1, FOXA1, DDX5, ZNF549, ERG, YY1, RELA, ZNF384, AHR, MYC, RAD21, ARNT, HIF1A, GATA3, STAT3, PAX5, ZNF143, MITF, MED1, PLAG1, NR3C1, NCOA3, ZNF680, CREB1, EZH2, ESR1, PKNOX1, OCA2, NCOA1, GRHL2, USF2, JUN, CTCF, USF1, SPI1, AR, ZNF479, FLI1, HSF1, RAD51, NOTCH3, BRD4, SMC3, STAG1, TFAP2C, EED

Target gene symbol (double-evidenced CRMs): TMPRSS2,RIPK4,FAM3B,PRDM15,MX1

Function elements

Human SNPs: .

Number of somatic mutations (coding): 0

Number of somatic mutations (non-coding): 0

Related genes and loops

Related gene: ENSG00000183844, ENSG00000157601, ENSG00000184012, ENSG00000183421, ENSG00000141956,

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Deatailed information for cohesin site CDBP00419960