- Basic information
- CohesinDB ID: CDBP00419961
- Locus: chr21-41312700-41313050
-
Data sourse: GSE111913, GSE67783, GSE120943, GSE98367
-
Cell type: Monocytes, RT-112, HSPC, Macrophage
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 1% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.956
- Subunit: SA1,SA2,SMC1
-
CTCF binding site: non-CTCF
CTCF motif: False
- Genomic location: Intragenic
- 3D genome
- TAD boundary: non-Boundary
- Chromatin hubs: Hub
-
Hi-C loops: True
Hi-ChIP loops: True
ChIA-PET loops: True
- Compartment:
81% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): False
-
Chromatin annotation:
"14_ReprPCWk": 75%,
"15_Quies": 15%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
-
Co-bound Transcriptional factors: TRIM25, PGR, SOX2, NME2, XBP1, FOXA1, SUZ12, RBFOX2, KDM3A, TFAP4, ATF3, ZFP64, CTCFL, CHD7, CBFB, MORC2, MXD4, TP63, ZNF586, KLF5, TRIM28, TEAD1, RBM39, KLF6, SNAI2, ESR1, CTCF, TCF12, BAF155, EP300, SOX5, RYBP, E2F6, TEAD4, GATAD2A, PDX1, TFAP2C, RBPJ, JARID2, NANOG, CHD8, BRD1, ZSCAN5D, POU5F1, MYCN, DUX4, ZBTB48, STAT1, NONO, SAP130, SP4, ERG, ASCL1, OGG1, ZNF25, MYC, KDM4A, RAD21, GRHL3, GABPA, MCRS1, STAT3, XRCC5, NKX3-1, PRDM14, NFE2, HNRNPH1, NR2F6, CEBPB, HNRNPL, CREB1, EZH2, BMPR1A, GRHL2, GABPB1, PHF8, SPI1, PCBP1, HDAC2, GATA2, ZNF644, MXD3, ZGPAT, NCOA2, ETV5, RUNX1, BCL6, MAFG, EZH2phosphoT487, SIRT6, NKX2-2, SOX13, ZFX, SIN3A, SMAD3, SP5, CREBBP, RARA, NFYC, TAF15, ARNT, NRF1, ZNF48, SMAD4, NCAPH2, CHD1, ZEB1, TEAD3, KDM6B, PIAS1, SMAD1, BCL11A, REST, ARID1A, ZBTB7A, POU2F3, ASH2L, HNRNPLL, CTBP2, BCOR, FOXP1, TCF3, AATF, SMC3, STAG1, TRP47, CBFA2T2, FOXA2, AGO1, RBBP5, HDAC6, CHD2, WT1, CDK9, HOXB13, ZNF580, KDM1A, YY1, RELA, TARDBP, MCM3, SP140, PCGF1, MAF1, MAX, NRIP1, ZNF143, AGO2, TLE3, BCL11B, NCOA3, NR2F1, KDM5B, TP53, ZNF547, BRD2, ELF3, ARID4B, AR, TAF1, RXR, HEXIM1, EGR1, TFIIIC, HSF1, ZBTB26, BRD4, MAZ, AHR
- Target gene symbol (double-evidenced CRMs): RIPK4,PRDM15,MX1,TMPRSS2,FAM3B
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 0
- Number of somatic mutations (non-coding): 0
- Related genes and loops
- Related gene:
ENSG00000183844,
ENSG00000157601,
ENSG00000184012,
ENSG00000183421,
ENSG00000141956,
- Related loop:
chr21:41300000-41325000~~chr21:41425000-41450000,
chr21:41300000-41325000~~chr21:41450000-41475000,
chr21:41300000-41325000~~chr21:41500000-41525000,
chr21:41300000-41325000~~chr21:41575000-41600000,
chr21:41300000-41325000~~chr21:41600000-41625000,
chr21:41300000-41325000~~chr21:41700000-41725000,
chr21:41300000-41325000~~chr21:41750000-41775000,
chr21:41300000-41325000~~chr21:41775000-41800000,
chr21:41300000-41325000~~chr21:41800000-41825000,
chr21:41300000-41325000~~chr21:41825000-41850000,