Deatailed information for cohesin site CDBP00419962

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  • Basic information
  • CohesinDB ID: CDBP00419962
  • Locus: chr21-41315579-41317852
  • Data sourse: ENCSR000BLD, ENCSR338DUC, GSE67783, GSE72082, GSE86191, GSE116868, ENCSR000BLS, GSE105028, GSE206145-NatGen2015, GSE206145, GSE131606, GSE126755
  • Cell type: RPE, H1-hESC, Fibroblast, HCT-116, Hep-G2, MB157, DKO, Neutrophil, HSPC, H9-hESC
  • DNA Sequence of binding site: UCSC hg38
  • Cohesin category
  • Peak occupancy ratio: 3% samples have this site.
  • Cell specificity (0: conserved, 1: cell type specific): 0.889
  • Subunit: SA1,Rad21,SMC1,SA2,SMC3
  • CTCF binding site: CTCF CTCF motif: False
  • Genomic location: Intragenic
  • 3D genome
  • TAD boundary: non-Boundary
  • Chromatin hubs: Hub
  • Hi-C loops: True Hi-ChIP loops: True ChIA-PET loops: True
  • Compartment: 81% Hi-C samples shows Compartment A
  • Cis-regulatory elements
  • Enhancer (Fantom5): non-Enhancer
  • Super enhancer (SEdb): False
  • Chromatin annotation: "13_ReprPC": 34%, "14_ReprPCWk": 17%,
    Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
  • Co-bound Transcriptional factors: TRIM25, PGR, SOX2, NME2, XBP1, FOXA1, SUZ12, RBFOX2, KDM3A, TFAP4, ATF3, ZFP64, CTCFL, CHD7, CBFB, MORC2, MXD4, TP63, ZNF586, KLF5, TRIM28, TEAD1, RBM39, KLF6, SNAI2, ESR1, CTCF, TCF12, BAF155, EP300, SOX5, RYBP, E2F6, TEAD4, GATAD2A, PDX1, TFAP2C, RBPJ, JARID2, NANOG, CHD8, BRD1, ZSCAN5D, POU5F1, MYCN, DUX4, ZBTB48, STAT1, NONO, SAP130, SP4, ERG, ASCL1, OGG1, ZNF25, MYC, KDM4A, RAD21, GRHL3, GABPA, MCRS1, STAT3, XRCC5, NKX3-1, PRDM14, NFE2, HNRNPH1, NR2F6, CEBPB, HNRNPL, CREB1, EZH2, BMPR1A, GRHL2, GABPB1, PHF8, SPI1, PCBP1, HDAC2, GATA2, ZNF644, MXD3, ZGPAT, NCOA2, ETV5, RUNX1, BCL6, MAFG, EZH2phosphoT487, SIRT6, NKX2-2, SOX13, ZFX, SIN3A, SMAD3, SP5, CREBBP, RARA, NFYC, TAF15, ARNT, NRF1, ZNF48, SMAD4, NCAPH2, CHD1, ZEB1, TEAD3, KDM6B, PIAS1, SMAD1, BCL11A, REST, ARID1A, ZBTB7A, POU2F3, ASH2L, HNRNPLL, CTBP2, BCOR, FOXP1, TCF3, AATF, SMC3, STAG1, TRP47, CBFA2T2, FOXA2, AGO1, RBBP5, HDAC6, CHD2, WT1, CDK9, HOXB13, ZNF580, KDM1A, YY1, RELA, TARDBP, MCM3, SP140, PCGF1, MAF1, MAX, NRIP1, ZNF143, AGO2, TLE3, BCL11B, NCOA3, NR2F1, KDM5B, TP53, ZNF547, BRD2, ELF3, ARID4B, AR, TAF1, RXR, HEXIM1, EGR1, TFIIIC, HSF1, ZBTB26, BRD4, MAZ, AHR
  • Target gene symbol (double-evidenced CRMs): FAM3B,RIPK4,PRDM15,MX1,TMPRSS2
  • Function elements
  • Human SNPs: Educational_attainment_(years_of_education)
  • Number of somatic mutations (coding): 21
  • Number of somatic mutations (non-coding): 7
  • Related genes and loops
  • Related gene: ENSG00000183844, ENSG00000157601, ENSG00000184012, ENSG00000183421, ENSG00000141956,
  • Related loop: chr21:41300000-41325000~~chr21:41425000-41450000, chr21:41300000-41325000~~chr21:41450000-41475000, chr21:41300000-41325000~~chr21:41500000-41525000, chr21:41300000-41325000~~chr21:41575000-41600000, chr21:41300000-41325000~~chr21:41600000-41625000, chr21:41300000-41325000~~chr21:41700000-41725000, chr21:41300000-41325000~~chr21:41750000-41775000, chr21:41300000-41325000~~chr21:41775000-41800000, chr21:41300000-41325000~~chr21:41800000-41825000, chr21:41300000-41325000~~chr21:41825000-41850000,
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