Deatailed information for cohesin site CDBP00419966

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  • Basic information
  • CohesinDB ID: CDBP00419966
  • Locus: chr21-41326476-41327101
  • Data sourse: GSE206145-GSE177045, ENCSR338DUC, ENCSR000EEG, GSE67783, ENCSR230ZWH, GSE86191, GSE111913
  • Cell type: MCF-7, HCT-116, Hep-G2, RT-112, Liver, HSPC
  • DNA Sequence of binding site: UCSC hg38
  • Cohesin category
  • Peak occupancy ratio: 2% samples have this site.
  • Cell specificity (0: conserved, 1: cell type specific): 0.933
  • Subunit: Mau2,SA1,Rad21,SA2
  • CTCF binding site: CTCF CTCF motif: False
  • Genomic location: Intragenic
  • 3D genome
  • TAD boundary: non-Boundary
  • Chromatin hubs: non-Hub
  • Hi-C loops: False Hi-ChIP loops: False ChIA-PET loops: True
  • Compartment: 81% Hi-C samples shows Compartment A
  • Cis-regulatory elements
  • Enhancer (Fantom5): non-Enhancer
  • Super enhancer (SEdb): True
  • Chromatin annotation: "15_Quies": 49%, "14_ReprPCWk": 29%,
    Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
  • Co-bound Transcriptional factors: NFIA, HMG20A, SOX2, XBP1, FOXA1, RBFOX2, RXRB, TFAP4, ATF3, ZFP64, MXD4, TP63, MAF, TEAD1, ELF1, RCOR2, ESR1, CTCF, JUN, EP300, SOX5, DMAP1, FOXA3, ZNF175, GATAD2A, RBPJ, TFAP2C, POU2F2, MYCN, POU5F1, ZBTB48, ZSCAN5A, GATAD1, SAP130, ARID3A, HNF4G, OGG1, ETS1, MYC, HOMEZ, RAD21, GRHL3, RXRA, STAT3, XRCC5, ZNF614, MIER3, HNRNPH1, NR2F6, CEBPB, HNRNPL, CCAR2, GRHL2, GABPB1, SPI1, TFE3, MIXL1, HBP1, HDAC2, ZNF644, MXD3, SIX2, DRAP1, ZGPAT, NFIL3, PTBP1, ETV5, RUNX1, THAP11, BCL6, CEBPA, SOX13, ZFX, FIP1L1, TET2, SMARCC1, RARA, PRPF4, NRF1, ZNF48, PRDM9, SMAD4, MED1, TEAD3, MYB, U2AF1, SETDB1, RBM22, SP1, HNF4A, IKZF5, ASH2L, FOXP1, AATF, STAG1, TRP47, MEF2B, FOXA2, AGO1, CREM, EBF1, WT1, TCF7, HOXB13, ZNF580, KDM1A, YY1, RELA, SP140, MAX, AGO2, CEBPG, KLF4, KDM5B, NFKB1, ELF3, KAT8, ARID4B, AR, NFKBIZ, HSF1, ZBTB26, JUND, BRD4, CUX1, MAZ, AHR, FOSL2
  • Target gene symbol (double-evidenced CRMs): FAM3B
  • Function elements
  • Human SNPs: Tumor_biomarkers
  • Number of somatic mutations (coding): 8
  • Number of somatic mutations (non-coding): 0
  • Related genes and loops
  • Related gene: ENSG00000183844,
  • Related loop: chr21:41300000-41325000~~chr21:41425000-41450000, chr21:41300000-41325000~~chr21:41450000-41475000, chr21:41300000-41325000~~chr21:41500000-41525000, chr21:41300000-41325000~~chr21:41575000-41600000, chr21:41300000-41325000~~chr21:41600000-41625000, chr21:41300000-41325000~~chr21:41700000-41725000, chr21:41300000-41325000~~chr21:41750000-41775000, chr21:41300000-41325000~~chr21:41775000-41800000, chr21:41300000-41325000~~chr21:41800000-41825000, chr21:41300000-41325000~~chr21:41825000-41850000,
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