- Basic information
- CohesinDB ID: CDBP00419986
- Locus: chr21-41381134-41381620
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Data sourse: GSE67783, GSE86191
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Cell type: HCT-116, HSPC
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 1% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.978
- Subunit: SA1,Rad21
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CTCF binding site: CTCF
CTCF motif: False
- Genomic location: Intragenic
- 3D genome
- TAD boundary: non-Boundary
- Chromatin hubs: Hub
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Hi-C loops: True
Hi-ChIP loops: False
ChIA-PET loops: True
- Compartment:
81% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): True
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Chromatin annotation:
"15_Quies": 33%,
"4_Tx": 24%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: RUNX1, NFATC3, TRP47, POU2F2, SMC1A, BRD1, PGR, MYCN, ZFX, ZBTB48, WT1, ZSCAN5A, SMAD3, TET2, ZBTB33, RBFOX2, CDK9, KDM3A, ERG, RELA, CREBBP, HDGF, OGG1, ATF3, RUNX2, MYC, RAD21, SP140, ARNT, HIF1A, GRHL3, TCF4, ZIC2, MAF1, MAX, TP63, NRIP1, ZNF143, AGO2, CDK8, DNMT3B, HNRNPH1, MED1, PLAG1, ZNF320, CEBPB, ZEB1, HNRNPL, MYB, TFAP2C, SNAI2, NR2F1, EZH2, SMAD1, ESR1, LMO2, NEUROG2, OCA2, NFKB1, CTCF, RBM22, SPI1, ZNF479, IRF4, MXD3, EGR1, HSF1, BRD4, MAZ, AATF, SMC1, SMC3, STAG1, AHR
- Target gene symbol (double-evidenced CRMs): TMPRSS2,MX2,FAM3B,BACE2
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 1
- Number of somatic mutations (non-coding): 1
- Related genes and loops